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FBXO21

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternative splicing of this gene generates 2 transcript variants.
Full Name
F-Box Protein 21
Research Area
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.
Biological Process
Ubiquitin-dependent protein catabolic process Source: UniProtKB
Cellular Location
Cytosol; Ubiquitin ligase complex

Anti-FBXO21 antibodies

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Target: FBXO21
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Mouse, Rat, Dog, Human, Monkey
Clone: 2C7
Application*: WB, P, F, IF
Target: FBXO21
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBXF-1110
Application*: WB, IP
Target: FBXO21
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBXF-1109
Application*: WB, IP, P, F, IF
Target: FBXO21
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3A6
Application*: WB
Target: FBXO21
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXF-3887
Application*: F, IF, IH, WB
Target: FBXO21
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 3C11
Application*: F, IF, P, WB
Target: FBXO21
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 5H4
Application*: F, IF, P, WB
Target: FBXO21
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 6C10
Application*: F, P, WB
Target: FBXO21
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXF-3594
Application*: F, IF, P, WB
Target: FBXO21
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Dog, Rat, Monkey
Clone: CBXF-3622
Application*: F, IF, P, WB
Target: FBXO21
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 4G5
Application*: F, IF, WB
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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