FOLR3

This gene encodes a member of the folate receptor (FOLR) family of proteins, which have a high affinity for folic acid and for several reduced folic acid derivatives, and mediate delivery of 5-methyltetrahydrofolate to the interior of cells. Expression of this gene may be elevated in ovarian and primary peritoneal carcinoma. This gene is present in a gene cluster on chromosome 11. Alternative splicing results in multiple transcript variants.

Folate Receptor 3

Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate to the interior of cells. Isoform Short does not bind folate.

Cell adhesion Source: GO_Central
Folic acid transport Source: ProtInc
Fusion of sperm to egg plasma membrane involved in single fertilization Source: GO_Central
Sperm-egg recognition Source: GO_Central

Secreted