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CD200

CD200 (CD200 Molecule) is a Protein Coding gene. Diseases associated with CD200 include Mantle Cell Lymphoma and Primary Hypertrophic Osteoarthropathy. Among its related pathways are Innate Immune System and Class I MHC mediated antigen processing and presentation.
Full Name
CD200 Molecule
Alternative Names
CD200 Molecule; CD200 Antigen; Antigen Identified By Monoclonal Antibody MRC OX-2; MOX1; MOX2; OX-2 Membrane Glycoprotein; OX-2; MRC;
Function
Costimulates T-cell proliferation. May regulate myeloid cell activity in a variety of tissues.
Biological Process
Cell-cell adhesion Source: ARUK-UCL
Heterotypic cell-cell adhesion Source: ARUK-UCL
Negative regulation of cell population proliferation Source: ARUK-UCL
Negative regulation of interleukin-6 production Source: ARUK-UCL
Negative regulation of leukocyte activation Source: ARUK-UCL
Negative regulation of macrophage activation Source: ARUK-UCL
Negative regulation of macrophage migration Source: ARUK-UCL
Negative regulation of matrix metallopeptidase secretion Source: ARUK-UCL
Negative regulation of neuroinflammatory response Source: ARUK-UCL
Negative regulation of neuron death Source: ARUK-UCL
Negative regulation of NF-kappaB transcription factor activity Source: ARUK-UCL
Negative regulation of T cell migration Source: ARUK-UCL
Positive regulation of arginase activity Source: ARUK-UCL
Positive regulation of CREB transcription factor activity Source: ARUK-UCL
Positive regulation of protein-glutamine gamma-glutamyltransferase activity Source: ARUK-UCL
Positive regulation of transforming growth factor beta production Source: ARUK-UCL
Regulation of immune response Source: Reactome
Regulation of neuroinflammatory response Source: ARUK-UCL
Cellular Location
Cell membrane
Topology
Extracellular: 31-232
Helical: 233-259
Cytoplasmic: 260-278

Anti-CD200 antibodies

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Target: CD200
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: AG11
Application*: F, IH, In Vivo
Target: CD200
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-1107
Application*: N
Target: CD200
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: OX-104
Application*: F
Target: CD200
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBYY-C0020
Application*: IF, IP, WB, F
Target: CD200
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBFYM-0972
Application*: IF, IP, WB, F
Target: CD200
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 333
Application*: P
Target: CD200
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 005
Application*: E
Target: CD200
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: 2
Application*: F
Target: CD200
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Mouse, Rat
Clone: OX2
Application*: IF, F, E
Target: CD200
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXO-0301
Application*: E, F
Target: CD200
Host: Rat
Antibody Isotype: IgG2a, κ
Specificity: Mouse
Clone: OX90
Application*: IF, F, IH, B
More Infomation
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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