CD200

CD200 (CD200 Molecule) is a Protein Coding gene. Diseases associated with CD200 include Mantle Cell Lymphoma and Primary Hypertrophic Osteoarthropathy. Among its related pathways are Innate Immune System and Class I MHC mediated antigen processing and presentation.
Full Name
CD200 Molecule
Alternative Names
CD200 Molecule; CD200 Antigen; Antigen Identified By Monoclonal Antibody MRC OX-2; MOX1; MOX2; OX-2 Membrane Glycoprotein; OX-2; MRC;
Function
Costimulates T-cell proliferation. May regulate myeloid cell activity in a variety of tissues.
Biological Process
Cell-cell adhesion Source: ARUK-UCL
Heterotypic cell-cell adhesion Source: ARUK-UCL
Negative regulation of cell population proliferation Source: ARUK-UCL
Negative regulation of interleukin-6 production Source: ARUK-UCL
Negative regulation of leukocyte activation Source: ARUK-UCL
Negative regulation of macrophage activation Source: ARUK-UCL
Negative regulation of macrophage migration Source: ARUK-UCL
Negative regulation of matrix metallopeptidase secretion Source: ARUK-UCL
Negative regulation of neuroinflammatory response Source: ARUK-UCL
Negative regulation of neuron death Source: ARUK-UCL
Negative regulation of NF-kappaB transcription factor activity Source: ARUK-UCL
Negative regulation of T cell migration Source: ARUK-UCL
Positive regulation of arginase activity Source: ARUK-UCL
Positive regulation of CREB transcription factor activity Source: ARUK-UCL
Positive regulation of protein-glutamine gamma-glutamyltransferase activity Source: ARUK-UCL
Positive regulation of transforming growth factor beta production Source: ARUK-UCL
Regulation of immune response Source: Reactome
Regulation of neuroinflammatory response Source: ARUK-UCL
Cellular Location
Cell membrane
Topology
Extracellular: 31-232
Helical: 233-259
Cytoplasmic: 260-278
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Anti-CD200 antibodies

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Rabbit Anti-CD200 Recombinant Antibody (2) (CBMAB-C0561-LY)

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Target: CD200
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse
Clone: 2
Application*: F
Datasheet SDS

Rat Anti-CD200 Recombinant Antibody (AG11) (V2LY-0524-LY86)

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Target: CD200
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: AG11
Application*: F, IH, In Vivo
In Vivo Assay
Datasheet SDS

Mouse Anti-CD200 Recombinant Antibody (CBT3316) (V2LY-0625-LY218)

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Target: CD200
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBT3316
Application*: WB
Datasheet SDS

Mouse Anti-CD200 Recombinant Antibody (CBT2730) (V2LY-0625-LY1739)

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Target: CD200
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBT2730
Application*: IC, F
Datasheet SDS

Mouse Anti-CD200 Recombinant Antibody (CBXC-1107) (CBMAB-C1373-CQ)

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Target: CD200
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-1107
Application*: N
Functional Assay
Datasheet SDS

Mouse Anti-CD200 Recombinant Antibody (OX-104) (CBMAB-C0967-CQ)

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Target: CD200
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: OX-104
Application*: F
Datasheet SDS

Mouse Anti-CD200 Recombinant Antibody (CBYY-C0020) (CBMAB-C0049-YY)

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Target: CD200
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBYY-C0020
Application*: IF, IP, WB, F
Datasheet SDS

Mouse Anti-CD200 Recombinant Antibody (CBFYM-0972) (CBMAB-M1122-FY)

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Target: CD200
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBFYM-0972
Application*: IF, IP, WB, F
Datasheet SDS

Rabbit Anti-CD200 Recombinant Antibody (333) (CBMAB-C5530-LY)

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Target: CD200
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 333
Application*: P
Datasheet SDS

Rabbit Anti-CD200 Recombinant Antibody (005) (CBMAB-C1518-LY)

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Target: CD200
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 005
Application*: E
Datasheet SDS

Mouse Anti-CD200 Recombinant Antibody (OX2) (CBMAB-O0787-CQ)

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Target: CD200
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Mouse, Rat
Clone: OX2
Application*: IF, F, E
Datasheet SDS

Mouse Anti-CD200 Recombinant Antibody (CBXO-0301) (CBMAB-O0786-CQ)

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Target: CD200
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXO-0301
Application*: E, F
Datasheet SDS

Rat Anti-CD200 Recombinant Antibody (OX90) (CBMAB-O0785-CQ)

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Target: CD200
Host: Rat
Antibody Isotype: IgG2a, κ
Specificity: Mouse
Clone: OX90
Application*: IF, F, IH, B
Functional Assay
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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