Sign in or Register   Sign in or Register
  |  

CD68

CD68 (CD68 Molecule) is a Protein Coding gene. Diseases associated with CD68 include Granular Cell Tumor and Breast Granular Cell Tumor. Among its related pathways are Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers and Innate Immune System. An important paralog of this gene is LAMP1.
Full Name
CD68 Molecule
Function
Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.
Biological Process
Aging Source: ARUK-UCL
Autocrine signaling Source: Ensembl
Cellular response to lipopolysaccharide Source: ARUK-UCL
Cellular response to nutrient levels Source: ARUK-UCL
Cellular response to oxidised low-density lipoprotein particle stimulus Source: ARUK-UCL
Establishment of protein localization to organelle Source: GO_Central
Inflammatory response to antigenic stimulus Source: ARUK-UCL
Negative regulation of dendritic cell antigen processing and presentation Source: ARUK-UCL
Neutrophil degranulation Source: Reactome
Cellular Location
Isoform Short: Cell membrane
Isoform Long: Lysosome membrane; Endosome membrane
Topology
Extracellular: 22-319
Helical: 320-344
Cytoplasmic: 345-354
PTM
N- and O-glycosylated.

Anti-CD68 antibodies

Loading...
Target: CD68
Host: Mouse
Antibody Isotype: IgG1
Specificity: Rat
Clone: CBFYA-0212
Application*: F, C, IP, P, WB
Target: CD68
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBFYA-0032
Application*: F, C, IF, IP, WB
Target: CD68
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBXC-1750
Application*: WB, IP, IF, P, E
Target: CD68
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CDLA68-1
Application*: F, P
Target: CD68
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXC-2581
Application*: IH, IF, P, C
Target: CD68
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-2817
Application*: E, IH
Target: CD68
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-2862
Application*: WB, F, E, IH, IF, MC
Target: CD68
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-2826
Application*: WB, IH
Target: CD68
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBXC-1388
Application*: F, IF, IH, IP, WB
Target: CD68
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: Y1/82A
Application*: F
Target: CD68
Host: Human
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-0938
Application*: F
Target: CD68
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXC-1072
Application*: WB
Target: CD68
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXC-1071
Application*: IS
Target: CD68
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: Y-2/131/47
Application*: WB
Target: CD68
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat, Cat
Clone: SPM130
Application*: WB, F, IF, IP, P, C
Target: CD68
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Rat, Cattle, Monkey
Clone: ED1
Application*: WB, F, IF, P, C
Target: CD68
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CD68/G2
Application*: F, P, IF
Target: CD68
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-1398
Application*: E
Target: CD68
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYC-1397
Application*: E
Target: CD68
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBFYC-1396
Application*: P
Target: CD68
Host: Rabbit
Antibody Isotype: IgG
Specificity: Rat
Clone: CBFYC-1395
Application*: P
Target: CD68
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBFYC-1394
Application*: WB
Target: CD68
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBFYC-0509
Application*: F
Target: CD68
Host: Mouse
Antibody Isotype: IgG1
Specificity: Rat
Clone: CBFYC-0172
Application*: F, IH, IP
Target: CD68
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBFYC-0171
Application*: F, IF, IH, IP, WB
Target: CD68
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 8A4
Application*: P, WB
Target: CD68
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 815CU17
Application*: P, WB
Target: CD68
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 7D3
Application*: P, WB
Target: CD68
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 6D3
Application*: WB
Target: CD68
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 6C3
Application*: WB
Target: CD68
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 6A10
Application*: WB
Target: CD68
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 4G1
Application*: P, WB
Target: CD68
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 4E3
Application*: WB
Target: CD68
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 4D8
Application*: WB
Target: CD68
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 404CT9.2.5
Application*: WB, E
Target: CD68
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 3H1642
Application*: IF, IH
Target: CD68
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3F7D3
Application*: WB, P, F, IC/IF
Target: CD68
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3F7C6
Application*: E, WB, P, IF/C, F
Target: CD68
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: 3F10E11
Application*: E, C, F
Target: CD68
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3B6
Application*: P, WB
Target: CD68
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3A9A7
Application*: E, IH
Target: CD68
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: 2K6
Application*: IH
Target: CD68
Host: Mouse
Antibody Isotype: IgG3
Specificity: Human
Clone: 2H10
Application*: P, WB
Target: CD68
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2B7
Application*: WB
Target: CD68
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 1E6
Application*: WB
Target: CD68
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 179
Application*: P
Target: CD68
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 175
Application*: E
Target: CD68
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 13H2
Application*: WB
Target: CD68
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 514H12
Application*: IC/IF, C, P
Target: CD68
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 10H10
Application*: WB
Target: CD68
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 10E4
Application*: WB
Target: CD68
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 06
Application*: E
Target: CD68
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 039
Application*: E
Target: CD68
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 01
Application*: P
Target: CD68
Host: Rabbit
Antibody Isotype: IgG
Specificity: Rat
Clone: 001
Application*: P
Target: CD68
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 298807
Application*: IS, IC, MC
Target: CD68
Host: Mouse
Antibody Isotype: IgG1
Specificity: Rat
Clone: 10B1909
Application*: F, IH, IP
Target: CD68
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: 10B1906
Application*: F, IF, IH, IP, WB
Target: CD68
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: LAMP4/824
Application*: FC, IF, IHC
Target: CD68
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Monkey
Clone: C68/684
Application*: FC, IF, IHC
Target: CD68
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: 129
Application*: ELISA, IHC
Target: CD68
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CAP420
Application*: IHC
Target: CD68
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CAP419
Application*: ELISA, IHC
Target: CD68
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CF081
Application*: ELISA, IHC
Target: CD68
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CB247A
Application*: ELISA, IHC
Target: CD68
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CB129
Application*: IF, FC
Target: CD68
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CB128
Application*: IF, FC
Target: CD68
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: KP1
Application*: FC
Target: CD68
Host: Mouse
Antibody Isotype: IgG1
Specificity: Rat
Clone: CBHb391
Application*: FC, IHC-F, IP, IHC-P, WB
Target: CD68
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBHb051
Application*: FC, IHC-F, IF, IP, WB
Target: CD68
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: KP-1
Application*: ELISA
Target: CD68
Host: Mouse
Specificity: Human
Clone: IHC068
Application*: IH
Target: CD68
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: UMAB150
Application*: P, WB
Target: CD68
Host: Mouse
Specificity: Human, Mouse, Rat
Clone: CBCNC-165
Application*: IH
Target: CD68
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 6A323
Application*: FC
Target: CD68
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: SP251
Application*: FC, P
Target: CD68
Host: Mouse
Antibody Isotype: IgG3, κ
Specificity: Human
Clone: 5G61
Application*: IH
Target: CD68
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYY-C1553
Application*: F
Target: CD68
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYY-C1551
Application*: P, WB
Target: CD68
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYY-C1550
Application*: WB
Target: CD68
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C1549
Application*: WB
Target: CD68
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYY-C1548
Application*: WB
Target: CD68
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C1547
Application*: P, WB
Target: CD68
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYY-C1546
Application*: WB
Target: CD68
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYY-C1545
Application*: WB
Target: CD68
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYY-C1544
Application*: IF, IH
Target: CD68
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, mouse
Clone: CBYY-C1543
Application*: E, IH, F
Target: CD68
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C1542
Application*: P, WB
Target: CD68
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C1541
Application*: E, IH
Target: CD68
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYY-C0672
Application*: IC, IF, P, WB
Target: CD68
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: 6F3
Application*: IH
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
Go to
Compare