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CGA

The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. The protein encoded by this gene is the alpha subunit and belongs to the glycoprotein hormones alpha chain family. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
Full Name
Glycoprotein Hormones, Alpha Polypeptide
Function
Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH, follitropin/follicle stimulating hormone/FSH and choriogonadotropin/CG. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways.
Biological Process
G protein-coupled receptor signaling pathway Source: UniProtKB
Negative regulation of inflammatory response to antigenic stimulus Source: Reactome
Peptide hormone processing Source: Reactome
Positive regulation of cell migration Source: BHF-UCL
Positive regulation of cell population proliferation Source: BHF-UCL
Positive regulation of steroid biosynthetic process Source: UniProtKB
Positive regulation of transcription by RNA polymerase II Source: BHF-UCL
Regulation of signaling receptor activity Source: UniProtKB
Regulation of transcription by RNA polymerase II Source: Reactome
Thyroid hormone generation Source: GO_Central
Cellular Location
Secreted

Anti-CGA antibodies

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Target: CGA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-0396
Application*: E, P, IP, R
Target: CGA
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBXC-2657
Application*: IH, WB
Target: CGA
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBXC-0397
Application*: E, WB
Target: CGA
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: F1
Application*: E
Target: CGA
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXC-2636
Application*: E
Target: CGA
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBXC-2746
Application*: WB, E
Target: CGA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C1935
Application*: E
Target: CGA
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYY-C1933
Application*: E, IH, WB
Target: CGA
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYY-C1932
Application*: E
Target: CGA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C1931
Application*: E, P, C
Target: CGA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C1930
Application*: E
Target: CGA
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYY-C1928
Application*: WB, IH
Target: CGA
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYY-C1927
Application*: E, P, WB
Target: CGA
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYH-2910
Application*: E, WB
Target: CGA
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBFYH-2936
Application*: E, IA
Target: CGA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYH-2934
Application*: E, LF
Target: CGA
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYH-2932
Application*: E
Target: CGA
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: P2D9
Application*: E, IP, R
Target: CGA
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBFYC-1780
Application*: E
Target: CGA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: CBFYC-1779
Application*: E, WB
Target: CGA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYH-0082
Application*: IP, E, R, AP
Target: CGA
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBFYH-0081
Application*: E, IA, LF
Target: CGA
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYH-0079
Application*: WB, P, PE
Target: CGA
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYH-0078
Application*: E, R, IA, WB
Target: CGA
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYH-0077
Application*: SE
Target: CGA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYH-0076
Application*: E, P, C, IF
Target: CGA
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYH-0075
Application*: E, WB, P, R
Target: CGA
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBFYH-0074
Application*: E, LF
Target: CGA
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBFYH-0073
Application*: E, IF
Target: CGA
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYH-0072
Application*: E, WB, P
Target: CGA
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBFYH-0070
Application*: E, LF, IA
Target: CGA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYH-0069
Application*: E, F
Target: CGA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYH-2859
Application*: E, IP, R
Target: CGA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYH-2937
Application*: WB, P
Target: CGA
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: HCGab/52
Application*: IHC
Target: CGA
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Mouse, Rat
Clone: CAP488
Application*: WB
Target: CGA
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: SPM553
Application*: FC, IF, IHC
Target: CGA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: INN-hFSH-132
Application*: WB, IP, E, P, R
Target: CGA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYH-2931
Application*: P
Target: CGA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: HCG1
Application*: E, R, RD
Target: CGA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYH-2930
Application*: P
Target: CGA
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYH-2929
Application*: C, P
Target: CGA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: ABM401
Application*: E, R, F
Target: CGA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYH-2928
Application*: E, WB, P, IF, F
Target: CGA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYH-0071
Application*: R
Target: CGA
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYH-0080
Application*: WB, P, IF
Target: CGA
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: INN-hFSH-158
Application*: WB, E, IA, R
Target: CGA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: INN-hCG-72
Application*: WB, E, R
Target: CGA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: INN-hCG-45
Application*: E, R
Target: CGA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: M1709LHa
Application*: E, F
Target: CGA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJL-153
Application*: E
Target: CGA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJL-152
Application*: E, IF
Target: CGA
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 02A01
Application*: E, WB
Target: CGA
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYR0387
Application*: E
Target: CGA
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: SPM552
Application*: IHC
Target: CGA
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CGA/414
Application*: FC, IF, IHC
Target: CGA
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Monkey, Mouse, Rat
Clone: SPM339
Application*: FC, IF, IHC
Target: CGA
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CGA/413
Application*: FC, IF, IHC
Target: CGA
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Rat
Clone: CHGA/798
Application*: FC, IF, IHC
Target: CGA
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CHGA/765
Application*: FC, IF, IHC
Target: CGA
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CHGA/777
Application*: FC, IF, IHC, WB
Target: CGA
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Monkey
Clone: SPM585
Application*: FC, IF, IHC
Target: CGA
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Monkey
Clone: PHE5
Application*: FC, IF, IHC
Target: CGA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXF-3206
Application*: E, R
Target: CGA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: 268
Application*: ELISA, IHC, WB
Target: CGA
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: 4B1
Application*: IHC
Target: CGA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: LK2H10
Application*: IHC
Target: CGA
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CAP487
Application*: IHC, WB
Target: CGA
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYR0574
Application*: E
Target: CGA
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYR0573
Application*: E
Target: CGA
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYR0572
Application*: E
Target: CGA
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYR0571
Application*: SE
Target: CGA
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYR0570
Application*: SE
Target: CGA
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBFYR0569
Application*: SE
Target: CGA
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBFYR0568
Application*: SE
Target: CGA
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYR0567
Application*: SE
Target: CGA
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYR0380
Application*: E
Target: CGA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: HCGa/53
Application*: P, WB
Target: CGA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: B181M
Application*: E, ED
Target: CGA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CH5
Application*: E, IP, R
Target: CGA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: F62/01
Application*: P, E, ED
Target: CGA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: FSH-1
Application*: EC, E
Target: CGA
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: INN-hCG-5
Application*: C, R, P
Target: CGA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: INN-hFSH100
Application*: E, R
Target: CGA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: INN-hFSH132
Application*: E, IP, R, P
Target: CGA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: ME.111
Application*: WB, E, P, R
Target: CGA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: F1 BGN/F62/01
Application*: E, P
Target: CGA
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBXF-3205
Application*: E, IP, WB
Target: CGA
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 1B10
Application*: E
Target: CGA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 210
Application*: R
Target: CGA
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 3209
Application*: E, P, WB
Target: CGA
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 381012
Application*: WB, IH
Target: CGA
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 3H8
Application*: E
Target: CGA
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 76G3
Application*: E
Target: CGA
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 77F12
Application*: SE
Target: CGA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 8-F-118
Application*: E, R
Target: CGA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 10K152
Application*: E
Target: CGA
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: ME.109
Application*: E, WB
Target: CGA
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: RM330
Application*: ELISA, IHC, WB
Target: CGA
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYR0378
Application*: E
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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