Mouse Anti-CGA Recombinant Antibody (CBT2981) (V2LY-0625-LY199)

Name: Mouse Anti-CGA Recombinant Antibody (CBT2981)
SKU: V2LY-0625-LY199
Rating: 5 (1 reviews)

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Tested Data

Mouse Anti-CGA Recombinant Antibody (CBT2981) (V2LY-0625-LY199) in WB

Mouse Anti-CGA Recombinant Antibody (CBT2981) (V2LY-0625-LY199) in ELISA

Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBT2981

Application

Immunogen

Purified recombinant fragment of human CGA (AA: 25-147) expressed in E. Coli.

Host Species

Mouse

Specificity

Human

Antibody Isotype

IgG1

Clonality

Monoclonal Antibody

Application Notes

Application	Note
WB	1:500-1:2,000
ELISA	1:10,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS

Preservative

Sodium azide

Concentration

Batch dependent

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

More Infomation

Target

Full Name

Glycoprotein Hormones, Alpha Polypeptide

Entrez Gene ID

1081

UniProt ID

P01215

Function

Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH, follitropin/follicle stimulating hormone/FSH and choriogonadotropin/CG. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways.

Biological Process

G protein-coupled receptor signaling pathway Source: UniProtKB
Negative regulation of inflammatory response to antigenic stimulus Source: Reactome
Peptide hormone processing Source: Reactome
Positive regulation of cell migration Source: BHF-UCL
Positive regulation of cell population proliferation Source: BHF-UCL
Positive regulation of steroid biosynthetic process Source: UniProtKB
Positive regulation of transcription by RNA polymerase II Source: BHF-UCL
Regulation of signaling receptor activity Source: UniProtKB
Regulation of transcription by RNA polymerase II Source: Reactome
Thyroid hormone generation Source: GO_Central

Cellular Location

Secreted

Luo, L., Liu, S., Zhang, D., Wei, F., Gu, N., Zeng, Y., ... & Xiang, T. (2020). Chromogranin A (CGA)-derived polypeptide (CGA47–66) inhibits TNF-α-induced vascular endothelial hyper-permeability through SOC-related Ca2+ signaling. Peptides, 131, 170297.

Moradi, S., & Ghorbian, S. (2019). Association the Study of between CGA rs6631A> T Gene Polymorphism with the Risk of Male Infertility. Pajouhan Scientific Journal, 18(1), 15-22.

Sani, N. M., Sheidai, M., Noormohammadi, Z., Kalhor, N., & Roozbahani, G. A. (2018). Study of association the single nucleotide polymorphisms (rs6631) in 3′-UTR CGA gene with male infertility in Iranian population. Gene Reports, 12, 61-65.

Jamalvandi, M., Motovali-Bashi, M., Amirmahani, F., Darvishi, P., & Goharrizi, K. J. (2018). Association of T/A polymorphism in miR-1302 binding site in CGA gene with male infertility in Isfahan population. Molecular biology reports, 45(4), 413-417.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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