DMC1

This gene encodes a member of the superfamily of recombinases (also called DNA strand-exchange proteins). Recombinases are important for repairing double-strand DNA breaks during mitosis and meiosis. This protein, which is evolutionarily conserved, is reported to be essential for meiotic homologous recombination and may thus play an important role in generating diversity of genetic information. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]

DNA Meiotic Recombinase 1

Participates in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks.

Chromosome organization involved in meiotic cell cycle Source: GO_Central
DNA recombinase assembly Source: GO_Central
Female gamete generation Source: ProtInc
Homologous chromosome pairing at meiosis Source: Ensembl
Male meiosis I Source: Ensembl
Meiotic cell cycle Source: ProtInc
Mitotic recombination Source: GO_Central
Oocyte maturation Source: Ensembl
Ovarian follicle development Source: Ensembl
Reciprocal meiotic recombination Source: UniProtKB
Spermatid development Source: Ensembl
Spermatogenesis Source: ProtInc
Strand invasion Source: GO_Central

Nucleus; Chromosome