F4/80

Orphan receptor involved in cell adhesion and probably in cell-cell interactions specifically involving cells of the immune system. May play a role in regulatory T-cells (Treg) development.

Full Name

adhesion G protein-coupled receptor E1

Research Area

Orphan receptor involved in cell adhesion and probably in cell-cell interactions specifically involving cells of the immune system. May play a role in regulatory T-cells (Treg) development.

Biological Process

Adaptive immune response Source: UniProtKB-KW
Adenylate cyclase-activating G protein-coupled receptor signaling pathway Source: GO_Central
Cell surface receptor signaling pathway Source: InterPro

Cellular Location

Cell membrane

Topology

Extracellular: 28-644
Helical: 645-672
Cytoplasmic: 673-679
Helical: 680-701
Extracellular: 702-711
Helical: 712-735
Cytoplasmic: 736-754
Helical: 755-776
Extracellular: 777-792
Helical: 793-821
Cytoplasmic: 822-839
Helical: 840-859
Extracellular: 860-874
Helical: 875-897
Cytoplasmic: 898-931

Anti-F4/80 antibodies

Rat Anti-F4/80 Recombinant Antibody (A3-1) (CBMAB-1015-LY)

Datasheet

SDS

Target: F4/80

Host: Rat

Antibody Isotype: IgG1

Specificity: Mouse, Human

Clone: A3-1

Application*: F

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)