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Rat Anti-F4/80 Recombinant Antibody (A3-1) (CBMAB-1015-LY)

This product is rat antibody recognizes mouse F4/80. The antibody A3-1 immunoassay techniques such as: FC.
See all F4/80 antibodies
Published Data
Fig.1 FA injection induces interstitial cell infiltration in transgenic line A homozygous mice.
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Fig.2 Generation and validation of transgenic mice with specific tubular GREM1 overexpression.
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Fig.3 CD11b+F4/80+ osteoclast precursors and CD11b+CD61+ osteoclasts were analyzed on days 0, 3 and 5.
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Fig.4 Expression of Notch receptors and ligands on CD11b+F4/80+ osteoclast precursors was analyzed by flow cytometry.
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Summary

Host Animal
Rat
Specificity
Mouse, Human
Clone
A3-1
Antibody Isotype
IgG1
Application
FC

Basic Information

Specificity
Mouse, Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
adhesion G protein-coupled receptor E1
Introduction
Orphan receptor involved in cell adhesion and probably in cell-cell interactions specifically involving cells of the immune system. May play a role in regulatory T-cells (Treg) development.
Entrez Gene ID
13733
UniProt ID
Q61549
Alternative Names
Emr1; Ly71; F4/80; Gpf480; TM7LN3; DD7A5-7; EGF-TM7; Adgre1
Research Area
Orphan receptor involved in cell adhesion and probably in cell-cell interactions specifically involving cells of the immune system. May play a role in regulatory T-cells (Treg) development.
Biological Process
Adaptive immune response Source: UniProtKB-KW
Adenylate cyclase-activating G protein-coupled receptor signaling pathway Source: GO_Central
Cell surface receptor signaling pathway Source: InterPro
Cellular Location
Cell membrane
Topology
Extracellular: 28-644
Helical: 645-672
Cytoplasmic: 673-679
Helical: 680-701
Extracellular: 702-711
Helical: 712-735
Cytoplasmic: 736-754
Helical: 755-776
Extracellular: 777-792
Helical: 793-821
Cytoplasmic: 822-839
Helical: 840-859
Extracellular: 860-874
Helical: 875-897
Cytoplasmic: 898-931
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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