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FCGR2A

This gene encodes one member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells. The protein encoded by this gene is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2008]
Full Name
Fc Fragment Of IgG Receptor IIa
Research Area
Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens.
Biological Process
Cell surface receptor signaling pathway Source: GO_Central
Immune system process Source: UniProtKB-KW
Regulation of immune response Source: GO_Central
Cellular Location
Cell membrane
Topology
Extracellular: 34-217
Helical: 218-240
Cytoplasmic: 241-317
PTM
Phosphorylated by SRC-type Tyr-kinases such as LYN, BLK, FYN, HCK and SYK.

Anti-FCGR2A antibodies

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Target: FCGR2A
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBWJC-3681
Application*: F, IF, FN
Target: FCGR2A
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBWJC-3680
Application*: IF, F
Target: FCGR2A
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: FUN-2
Application*: F, IH
Target: FCGR2A
Host: Rabbit
Antibody Isotype: IgG
Specificity: Rat, Human
Clone: CBWJC-3678
Application*: WB, P
Target: FCGR2A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJC-3673
Application*: IF, P, IP, WB
Target: FCGR2A
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBWJC-2154
Application*: F
Target: FCGR2A
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: IV.3
Application*: F
Target: FCGR2A
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human, Baboon, Monkey
Clone: CBWJC-2153
Application*: F
Target: FCGR2A
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Cattle
Clone: CBWJC-2151
Application*: F, IH
Target: FCGR2A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Cattle, Sheep
Clone: CCG36
Application*: F, IH
Target: FCGR2A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Dog, Pig, Monkey, Human
Clone: AT10
Application*: C, IP, F, FN
Target: FCGR2A
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 2E10
Application*: E, IH, WB
Target: FCGR2A
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXC-2183
Application*: E, WB
Target: FCGR2A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-2176
Application*: F
Target: FCGR2A
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXC-2095
Application*: F
Target: FCGR2A
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYY-C2485
Application*: F, P, IP, WB
Target: FCGR2A
Host: Rat
Antibody Isotype: IgG2b
Specificity: Mouse
Clone: CBYY-C2484
Application*: F
Target: FCGR2A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C2483
Application*: E
Target: FCGR2A
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: CBYY-C2482
Application*: F, WB
Target: FCGR2A
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYY-C2481
Application*: E, WB
Target: FCGR2A
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 6C4 (CD32)
Application*: F, FN
Target: FCGR2A
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYY-C0534
Application*: F
Target: FCGR2A
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYY-C0263
Application*: IF, F
Target: FCGR2A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Dog, Human, Monkey, Pig
Clone: CBYY-C0106
Application*: F, IH, IP
Target: FCGR2A
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYC-2676
Application*: WB
Target: FCGR2A
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBFYC-2675
Application*: IP, IF, WB, P
Target: FCGR2A
Host: Rabbit
Antibody Isotype: IgG
Specificity: Monkey
Clone: CBFYC-2674
Application*: E
Target: FCGR2A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-2673
Application*: P, IP, WB
Target: FCGR2A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-2672
Application*: IF, P, WB
Target: FCGR2A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-2671
Application*: F, IF, P, IP, WB
Target: FCGR2A
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBFYC-0085
Application*: F
Target: FCGR2A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Monkey
Clone: 10A6C2
Application*: E, WB
Target: FCGR2A
Host: Mouse
Antibody Isotype: IgG
Specificity: Monkey
Clone: 09
Application*: EC
Target: FCGR2A
Host: Rabbit
Antibody Isotype: IgG
Specificity: Monkey
Clone: 085
Application*: E
Target: FCGR2A
Host: Mouse
Antibody Isotype: IgG
Specificity: Monkey
Clone: 02
Application*: ED
Target: FCGR2A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Monkey
Clone: 01
Application*: E
Target: FCGR2A
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 20
Application*: F
Target: FCGR2A
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: EG1184
Application*: WB: 1:500~1:1000 ELISA: 1:20000
Target: FCGR2A
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: A132
Application*: FC
Target: FCGR2A
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CB207
Application*: IF, FC
Target: FCGR2A
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CB206
Application*: IF, FC
Target: FCGR2A
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CB205
Application*: IF, FC
Target: FCGR2A
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 1F3-D1
Application*: F
Target: FCGR2A
Host: Rat
Antibody Isotype: IgG2b
Specificity: Mouse
Clone: 6A284
Application*: F
Target: FCGR2A
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: MM0270-3L1
Application*: WB, F
Target: FCGR2A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 7H135
Application*: FC
Target: FCGR2A
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: 14L197
Application*: FC, WB
Target: FCGR2A
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 11D38
Application*: FC
Target: FCGR2A
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBWJC-3684
Application*: F
Target: FCGR2A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 7D7G8B6
Application*: E, WB
Target: FCGR2A
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 6D11
Application*: F, P, IP, WB
Target: FCGR2A
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 3E8
Application*: E, WB
Target: FCGR2A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3D3
Application*: F
Target: FCGR2A
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 2E1
Application*: C, E, P, F
Target: FCGR2A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2C3B11B8
Application*: E
Target: FCGR2A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 19C10
Application*: F, IC/IF, P, IP, WB
Target: FCGR2A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 16E7
Application*: IF, P, WB
Target: FCGR2A
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 020
Application*: WB
Target: FCGR2A
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 13D7
Application*: IF, IH, IP, WB
Target: FCGR2A
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXF-0019
Application*: SE, E, WB
Target: FCGR2A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 9G5
Application*: WB, IH, IF, IP
Target: FCGR2A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 13G9
Application*: WB, IH, IF, F
Target: FCGR2A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXF-1279
Application*: IH
Target: FCGR2A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 6H7
Application*: WB, IH, IP
Target: FCGR2A
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXF-3659
Application*: F, IH, WB
Target: FCGR2A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXF-2115
Application*: E
Target: FCGR2A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Monkey
Clone: 20D1
Application*: IH, WB
Target: FCGR2A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 16D6
Application*: F, IF, IH, WB
Target: FCGR2A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXF-2532
Application*: E, WB
Target: FCGR2A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXF-2502
Application*: WB, IH, IF
Target: FCGR2A
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBXF-3459
Application*: F, FN
Target: FCGR2A
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 7.3
Application*: F, IF, MC
Target: FCGR2A
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: CBXF-2461
Application*: WB, F, MC
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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