GPR176

Members of the G protein-coupled receptor family, such as GPR176, are cell surface receptors involved in responses to hormones, growth factors, and neurotransmitters.

Full Name

G protein-coupled receptor 176

Function

Orphan receptor involved in normal circadian rhythm behavior. Acts through the G-protein subclass G(z)-alpha and has an agonist-independent basal activity to repress cAMP production.

Biological Process

Adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway Source: Ensembl
Chemical synaptic transmission Source: ProtInc
Circadian behavior Source: UniProtKB
G protein-coupled receptor signaling pathway Source: UniProtKB

Cellular Location

Cell membrane

Topology

Extracellular: 1-42
Helical: 43-63
Cytoplasmic: 64-82
Helical: 83-103
Extracellular: 104-118
Helical: 119-139
Cytoplasmic: 140-160
Helical: 161-181
Extracellular: 182-207
Helical: 208-228
Cytoplasmic: 229-267
Helical: 268-288
Extracellular: 289-299
Helical: 300-320
Cytoplasmic: 321-515

Anti-GPR176 antibodies

Rabbit Anti-GPR176 Recombinant Antibody (EG1395) (CBMAB-EN1674-LY)

Datasheet

SDS

Target: GPR176

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human, Mouse, Rat

Clone: EG1395

Application*: WB: 1:500~1:1000 IF: 1:100~1:500 ELISA: 1:10000

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)