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Rabbit Anti-GPR176 Recombinant Antibody (EG1395) (CBMAB-EN1674-LY)


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Summary

Host Animal
Rabbit
Specificity
Human, Mouse, Rat
Clone
EG1395
Antibody Isotype
IgG
Application
WB: 1:500~1:1000 IF: 1:100~1:500 ELISA: 1:10000

Basic Information

Immunogen
The antibody was produced against synthesized peptide derived from C-terminal of human GPR176.
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Introduction
Members of the G protein-coupled receptor family, such as GPR176, are cell surface receptors involved in responses to hormones, growth factors, and neurotransmitters.
Entrez Gene ID
Human11245
Mouse381413
Rat117257
UniProt ID
HumanQ14439
MouseQ80WT4
RatQ64017
Alternative Names
HB-954
Function
Orphan receptor involved in normal circadian rhythm behavior. Acts through the G-protein subclass G(z)-alpha and has an agonist-independent basal activity to repress cAMP production.
Biological Process
Adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway Source: Ensembl
Chemical synaptic transmission Source: ProtInc
Circadian behavior Source: UniProtKB
G protein-coupled receptor signaling pathway Source: UniProtKB
Cellular Location
Cell membrane
Topology
Extracellular: 1-42
Helical: 43-63
Cytoplasmic: 64-82
Helical: 83-103
Extracellular: 104-118
Helical: 119-139
Cytoplasmic: 140-160
Helical: 161-181
Extracellular: 182-207
Helical: 208-228
Cytoplasmic: 229-267
Helical: 268-288
Extracellular: 289-299
Helical: 300-320
Cytoplasmic: 321-515
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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