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UCN2

This gene is a member of the sauvagine/corticotropin-releasing factor/urotensin I family. It is structurally related to the corticotropin-releasing factor (CRF) gene and the encoded product is an endogenous ligand for CRF type 2 receptors. In the brain it may be responsible for the effects of stress on appetite. In spite of the gene family name similarity, the product of this gene has no sequence similarity to urotensin II. [provided by RefSeq, Jul 2008]
Full Name
Urocortin 2
Function
Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress.
Biological Process
Biological Process adenylate cyclase-activating G protein-coupled receptor signaling pathway Source:UniProtKB1 Publication
Biological Process cellular response to nutrient levels Source:GO_Central1 Publication
Biological Process digestion Source:UniProtKB1 Publication
Biological Process hormone-mediated signaling pathway Source:UniProtKB1 Publication
Cellular Location
Secreted
PTM
Glycosylated.

Anti-UCN2 antibodies

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Target: UCN2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBHb345
Application*: Immuno assays, WB
Target: UCN2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYA-0244
Application*: IA, WB
Target: UCN2
Host: Mouse
Specificity: Rat
Clone: CBCNC-735
Application*: WB, ICC, P, IH-F, E
Target: UCN2
Host: Mouse
Specificity: Human
Clone: CBCNC-734
Application*: WB, ICC, P, IH-F, E
Target: UCN2
Host: Mouse
Specificity: human
Clone: UII-9
Application*: WB, IP, E
Target: UCN2
Host: Mouse
Specificity: human
Clone: UII-6
Application*: WB, IP, E
Target: UCN2
Host: Mouse
Specificity: human
Clone: UII-13
Application*: WB, IP, E
Target: UCN2
Host: Mouse
Specificity: Human
Clone: 15j227
Application*: E, IF, IH, WB
Target: UCN2
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBCNC-112
Application*: ICC, P, E, WB
More Infomation
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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