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Mouse Anti-UCN2 Recombinant Antibody (15j227) (CBMAB-C4492-CN)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
15j227
Application
ELISA, IF, IHC, WB

Basic Information

Immunogen
Recombinant protein corresponding to aa 20-112 with an N-Terminal His-Tag from human UCN2, expressed in E. coli
Specificity
Human
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.4, 50% glycerol
Preservative
0.02% Sodium azide
Concentration
0.5 mg/mL

Target

Full Name
Urocortin 2
Introduction
This gene is a member of the sauvagine/corticotropin-releasing factor/urotensin I family. It is structurally related to the corticotropin-releasing factor (CRF) gene and the encoded product is an endogenous ligand for CRF type 2 receptors. In the brain it may be responsible for the effects of stress on appetite. In spite of the gene family name similarity, the product of this gene has no sequence similarity to urotensin II. [provided by RefSeq, Jul 2008]
Entrez Gene ID
90226
UniProt ID
Q96RP3
Alternative Names
Urocortin 2; Stresscopin-Related Peptide; Urocortin-Related Peptide; Prepro-Urocortin 2; Urocortin II; Ucn II; SRP;
Function
Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress.
Biological Process
Biological Process adenylate cyclase-activating G protein-coupled receptor signaling pathway Source:UniProtKB1 Publication
Biological Process cellular response to nutrient levels Source:GO_Central1 Publication
Biological Process digestion Source:UniProtKB1 Publication
Biological Process hormone-mediated signaling pathway Source:UniProtKB1 Publication
Cellular Location
Secreted
PTM
Glycosylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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