RBP1
This gene encodes the carrier protein involved in the transport of retinol (vitamin A alcohol) from the liver storage site to peripheral tissue. Vitamin A is a fat-soluble vitamin necessary for growth, reproduction, differentiation of epithelial tissues, and vision. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
Full Name
Retinol Binding Protein 1
Function
Cytoplasmic retinol-binding protein (PubMed:22665496, PubMed:26900151, PubMed:28057518).
Accepts retinol from the transport protein STRA6, and thereby contributes to retinol uptake, storage and retinoid homeostasis (PubMed:15632377, PubMed:22665496).
Accepts retinol from the transport protein STRA6, and thereby contributes to retinol uptake, storage and retinoid homeostasis (PubMed:15632377, PubMed:22665496).
Biological Process
Biological Process fatty acid transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process lipid homeostasisManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process retinoic acid biosynthetic processIEA:InterPro
Biological Process vitamin A metabolic processManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process lipid homeostasisManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process retinoic acid biosynthetic processIEA:InterPro
Biological Process vitamin A metabolic processManual Assertion Based On ExperimentIMP:UniProtKB
Cellular Location
Cytoplasm
Lipid droplet
Lipid droplet
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Anti-RBP1 antibodies
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Target: RBP1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Rat, Rabbit, Goat, Monkey
Clone: G4E4
Application*: P, IF
Target: RBP1
Host: Mouse
Specificity: Human
Clone: CBCNR-324
Application*: WB, ICC, P, C, E
Target: RBP1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 2H3
Application*: WB, P, F, IF
Target: RBP1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 2E1
Application*: WB, P, IF, F
Target: Rbp1
Sensitivity: 0.0077 ng/mL
Detection Range: 0.015-3 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Rat
Assay Type: Sandwich
Reactivity: Rat
Target: RBP1
Sensitivity: 1.12 ng/mL
Detection Range: 2-600 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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