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TNNI2

Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.

Full Name

Troponin I Type 2 (Skeletal, Fast)

Function

Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.

Biological Process

Biological Process cardiac muscle contraction Source:GO_Central1 Publication
Biological Process muscle contraction Source:GO_Central1 Publication
Biological Process positive regulation of DNA-templated transcription Source:UniProtKB1 Publication
Biological Process regulation of muscle contraction Source:Ensembl
Biological Process skeletal muscle contraction Source:UniProtKB1 Publication

Cellular Location

cytosol
nucleus
troponin complex

Involvement in disease

Arthrogryposis, distal, 2B1 (DA2B1):
A form of distal arthrogryposis, a disease characterized by congenital joint contractures that mainly involve two or more distal parts of the limbs, in the absence of a primary neurological or muscle disease. DA2B is characterized by contractures of the hands and feet, and a distinctive face characterized by prominent nasolabial folds, small mouth and downslanting palpebral fissures. DA2B1 inheritance is autosomal dominant.

Anti-TNNI2 antibodies

Mouse Anti-TNNI2 Recombinant Antibody (CBXF-2530) (CBMAB-F1150-CQ)

SDS

Target: TNNI2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXF-2530

Application*: P, F, E, IF, WB

Mouse Anti-TNNI2 Recombinant Antibody (CBYJT-4071) (CBMAB-T3487-YJ)

SDS

Target: TNNI2

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBYJT-4071

Application*: E, WB

Mouse Anti-TNNI2 Recombinant Antibody (11E6) (CBMAB-T3489-YJ)

SDS

Target: TNNI2

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: 11E6

Application*: E, WB, IH

Mouse Anti-TNNI2 Recombinant Antibody (CBYJT-4075) (CBMAB-T3493-YJ)

SDS

Target: TNNI2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYJT-4075

Application*: WB

Mouse Anti-TNNI2 Recombinant Antibody (2F12A8) (CBMAB-T3496-YJ)

SDS

Target: TNNI2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 2F12A8

Application*: E, F, IH, P, WB

Mouse Anti-TNNI2 Recombinant Antibody (2F12G2) (CBMAB-T3497-YJ)

SDS

Target: TNNI2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 2F12G2

Application*: E, F, IC, IF, WB

Mouse Anti-TNNI2 Recombinant Antibody (CBYJT-4077) (CBMAB-T3498-YJ)

SDS

Target: TNNI2

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBYJT-4077

Application*: WB, IH

Mouse Anti-TNNI2 Recombinant Antibody (CBYJT-4081) (CBMAB-T3502-YJ)

SDS

Target: TNNI2

Host: Mouse

Antibody Isotype: IgG

Specificity: Human, Rat, Mouse

Clone: CBYJT-4081

Application*: WB, IP, IF, E

Mouse Anti-TNNI2 Recombinant Antibody (CBXF-2529) (CBMAB-F1149-CQ)

SDS

Target: TNNI2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXF-2529

Application*: F, E, P, WB

Mouse Anti-TNNI2 Recombinant Antibody (CBYJT-4072) (CBMAB-T3490-YJ)

SDS

Target: TNNI2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYJT-4072

Application*: E, F, IH, WB

Mouse Anti-TNNI2 Recombinant Antibody (CBYJT-4074) (CBMAB-T3492-YJ)

SDS

Target: TNNI2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYJT-4074

Application*: E, F, WB

Mouse Anti-TNNI2 Recombinant Antibody (CBYJT-4076) (CBMAB-T3494-YJ)

SDS

Target: TNNI2

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBYJT-4076

Application*: E, WB

Mouse Anti-TNNI2 Recombinant Antibody (CBYJT-4078) (CBMAB-T3499-YJ)

SDS

Target: TNNI2

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBYJT-4078

Application*: E, WB, IF, IC, F

Mouse Anti-TNNI2 Recombinant Antibody (CBXF-2528) (CBMAB-F1148-CQ)

SDS

Target: TNNI2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXF-2528

Application*: E, P, WB

Mouse Anti-TNNI2 Recombinant Antibody (CBYJT-4082) (CBMAB-T3503-YJ)

SDS

Target: TNNI2

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Rabbit

Clone: CBYJT-4082

Application*: E, WB

Mouse Anti-TNNI2 Recombinant Antibody (CBYC-A1075) (CBMAB-A4883-YC)

SDS

Target: TNNI2

Host: Mouse

Antibody Isotype: IgG

Specificity: Rat

Clone: CBYC-A1075

Application*: WB, IC, P, C, E

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)

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