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Mouse Anti-TNNI2 Recombinant Antibody (CBYJT-4082) (CBMAB-T3503-YJ)


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Summary

Host Animal
Mouse
Specificity
Rabbit
Clone
CBYJT-4082
Antibody Isotype
IgG2b
Application
ELISA, WB

Basic Information

Immunogen
TNNI2 antibody was raised against rabbit Skeletal muscle Troponin I.
Specificity
Rabbit
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.5
Preservative
0.1% Sodium Azide
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Troponin I Type 2 (Skeletal, Fast)
Introduction
Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
Entrez Gene ID
100009581
UniProt ID
P02643
Alternative Names
TnI
Function
Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
Biological Process
Biological Process cardiac muscle contraction Source:GO_Central1 Publication
Biological Process muscle contraction Source:GO_Central1 Publication
Biological Process positive regulation of DNA-templated transcription Source:UniProtKB1 Publication
Biological Process regulation of muscle contraction Source:Ensembl
Biological Process skeletal muscle contraction Source:UniProtKB1 Publication
Cellular Location
cytosol
nucleus
troponin complex
Involvement in disease
Arthrogryposis, distal, 2B1 (DA2B1):
A form of distal arthrogryposis, a disease characterized by congenital joint contractures that mainly involve two or more distal parts of the limbs, in the absence of a primary neurological or muscle disease. DA2B is characterized by contractures of the hands and feet, and a distinctive face characterized by prominent nasolabial folds, small mouth and downslanting palpebral fissures. DA2B1 inheritance is autosomal dominant.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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