NCAM1
This gene encodes a cell adhesion protein which is a member of the immunoglobulin superfamily. The encoded protein is involved in cell-to-cell interactions as well as cell-matrix interactions during development and differentiation. The encoded protein has been shown to be involved in development of the nervous system, and for cells involved in the expansion of T cells and dendritic cells which play an important role in immune surveillance. Alternative splicing results in multiple transcript variants.
Full Name
Neural Cell Adhesion Molecule 1
Alternative Names
Neural Cell Adhesion Molecule 1; NCAM; Antigen Recognized By Monoclonal Antibody 5.1H11; Neural Cell Adhesion Molecule, NCAM; CD56 Antigen; N-CAM-1; NCAM-1; MSK39; CD56;
Function
This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc.
(Microbial infection) Acts as a receptor for rabies virus.
(Microbial infection) Acts as a receptor for Zika virus.
(Microbial infection) Acts as a receptor for rabies virus.
(Microbial infection) Acts as a receptor for Zika virus.
Biological Process
Cell adhesion Source: ProtInc
Commissural neuron axon guidance Source: ARUK-UCL
Regulation of semaphorin-plexin signaling pathway Source: ARUK-UCL
Commissural neuron axon guidance Source: ARUK-UCL
Regulation of semaphorin-plexin signaling pathway Source: ARUK-UCL
Cellular Location
Isoform 1&2&3&4: Cell membrane
Isoform 5&6: Secreted
Isoform 5&6: Secreted
Topology
Extracellular: 20-718
Helical: 719-739
Cytoplasmic: 740-858
Helical: 719-739
Cytoplasmic: 740-858
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Anti-NCAM1 antibodies
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CompareTarget: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBHb209
Application*: FC, IHC-F
Target: NCAM1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: MRQ-42
Application*: ELISA
Target: NCAM1
Host: Mouse
Specificity: Human
Clone: IHC056
Application*: P, E, IH
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBWJC-2344
Application*: F, P
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: T199
Application*: F, C
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: HCD56
Application*: IH, F
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Rat, Mouse
Clone: 5B8
Application*: E
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: AG141
Application*: DB, E, IH, In Vivo, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Mouse
Clone: CF304
Application*: ELISA, WB, IHC
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBT2975
Application*: WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: CBT4237
Application*: WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBT3638
Application*: WB, F
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT4342
Application*: WB, IH, F
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: A1307
Application*: IF, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: A1306
Application*: ICC, IHC
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: A1305
Application*: IF, IHC, IP
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: A1304
Application*: ICC, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: A1303
Application*: FC, ICC, IHC, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: A1302
Application*: ELISA, FC, IF, IHC, IP, RIA, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: A1301
Application*: ELISA, IHC, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Zebrafish
Clone: A1300
Application*: ICC, IHC, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: A1299
Application*: ELISA, FC, ICC, IHC, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CB321
Application*: IF, FC
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CB320
Application*: IF, FC
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CB319
Application*: IF, FC
Target: NCAM1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: RM315
Application*: IHC, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBHb208
Application*: IHC-F, IF, IHC-P
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 2G5-D6
Application*: F
Target: NCAM1
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: H28-123
Application*: IP, FN, C, IC/IF, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: NCAM1/784
Application*: F
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Monkey
Clone: TULY56
Application*: F
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: NCAM16
Application*: F
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYA-0137
Application*: F, C
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYA-0136
Application*: C, IF, P
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 5F303
Application*: IF, IH, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: 14L223
Application*: E, FC, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 10B1836
Application*: FC
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1.BB.490
Application*: FC, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 5K269
Application*: FC
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3H1567
Application*: E, IH, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Rat
Clone: IML-43
Application*: IC, WB
Target: NCAM1
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBWJC-4238
Application*: IF, IP, WB, F
Target: NCAM1
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBWJC-4237
Application*: IP, FN, C, IC, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJC-4236
Application*: F, IF, P, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJC-4232
Application*: IH
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJC-2345
Application*: F, IF
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBWJC-2343
Application*: F
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBWJC-2342
Application*: F, C
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBWJC-2341
Application*: F, E
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Rat, Zebrafish
Clone: CBXC-1415
Application*: E, F, IF, IH, IP, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-1805
Application*: F
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: NCAM1/1496
Application*: P
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: SPM489
Application*: IF, IH
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: NCAM1/795
Application*: F, IF, WB, P
Target: NCAM1
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBXC-1686
Application*: F
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: MEM-188
Application*: F
Target: NCAM1
Host: Human
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-0737
Application*: F
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYY-C1511
Application*: E, F
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Pig
Clone: CBYY-C1510
Application*: F
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Rat
Clone: CBYY-C1508
Application*: F, IC, IF, P, WB
Target: NCAM1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBYY-C1507
Application*: F, IC, IF, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYY-C1505
Application*: IH, IP, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYY-C1504
Application*: E, WB
Target: NCAM1
Host: Mouse
Specificity: Human
Clone: CBYY-C1503
Application*: IH
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C0632
Application*: E, F, IH, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYY-C0484
Application*: IC, IF, P, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYY-C0458
Application*: F
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C0399
Application*: F, IF
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYY-C0133
Application*: F, IP, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYY-C0057
Application*: F
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse
Clone: CBYY-C0016
Application*: E, WB
Target: NCAM1
Host: Rat
Antibody Isotype: IgM
Specificity: Mouse, Human, Rat
Clone: CBFYC-2996
Application*: WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Rat
Clone: CBFYC-2995
Application*: IC, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-0246
Application*: E, WB, P, C, F
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-0166
Application*: E, F, IH
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: CBFYM-3026
Application*: F, IC, C, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 7H185
Application*: E, F, C, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 5tukon56
Application*: P, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 5F47
Application*: F, IF
Target: NCAM1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: 3H15L12
Application*: F, IC, IF, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 3G85
Application*: IH, IP, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: 3F97
Application*: IH
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Pig
Clone: 2Q692
Application*: E, C, WB
Target: NCAM1
Host: Rat
Antibody Isotype: IgM
Specificity: Mouse, Human, Rat
Clone: 12F8
Application*: WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Rat, Human
Clone: 10K139
Application*: C, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 3H1571
Application*: F, IP, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 39D5
Application*: F
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Rat
Clone: 123C3.D5
Application*: E, F, IF, IH, IP, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 10B1827
Application*: E, F, IH
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJN-1198
Application*: IH
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJN-1197
Application*: P
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBWJN-1196
Application*: IH
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBWJN-1195
Application*: P
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: CBWJN-0726
Application*: IC, WB
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: MY31
Application*: F
Target: NCAM1
Host: Rabbit
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJN-0694
Application*: IH
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: MOC-1
Application*: F, IC, C
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: CBWJN-0682
Application*: WB, E, F
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: LT56
Application*: F
Target: NCAM1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Rat
Clone: CBWJN-0613
Application*: IC, WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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