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Mouse Anti-NCAM1 Recombinant Antibody (MEM-188) (CBMAB-C2203-CQ)

This product is a mouse antibody that recognizes NCAM1. The antibody MEM-188 can be used for immunoassay techniques such as: FC.
See all NCAM1 antibodies
Published Data
Fig.1 CD56 expression was sorted by flow cytometry.
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Fig.2 Schematic representation of the anti–IL-15 treatment schedule used in this study.
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Summary

Host Animal
Mouse
Specificity
Human
Clone
MEM-188
Antibody Isotype
IgG2a
Application
FC

Basic Information

Specificity
Human
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Neural Cell Adhesion Molecule 1
Introduction
This gene encodes a cell adhesion protein which is a member of the immunoglobulin superfamily. The encoded protein is involved in cell-to-cell interactions as well as cell-matrix interactions during development and differentiation. The encoded protein has been shown to be involved in development of the nervous system, and for cells involved in the expansion of T cells and dendritic cells which play an important role in immune surveillance. Alternative splicing results in multiple transcript variants.
Entrez Gene ID
4684
UniProt ID
P13591
Alternative Names
Neural Cell Adhesion Molecule 1; NCAM; Antigen Recognized By Monoclonal Antibody 5.1H11; Neural Cell Adhesion Molecule, NCAM; CD56 Antigen; N-CAM-1; NCAM-1; MSK39; CD56;
Function
This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc.

(Microbial infection) Acts as a receptor for rabies virus.

(Microbial infection) Acts as a receptor for Zika virus.
Biological Process
Cell adhesion Source: ProtInc
Commissural neuron axon guidance Source: ARUK-UCL
Regulation of semaphorin-plexin signaling pathway Source: ARUK-UCL
Cellular Location
Isoform 1&2&3&4: Cell membrane
Isoform 5&6: Secreted
Topology
Extracellular: 20-718
Helical: 719-739
Cytoplasmic: 740-858
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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