Mouse Anti-ABI3BP Recombinant Antibody (V2-347930) (CBMAB-T0001-YJ)

Name: Mouse Anti-ABI3BP Recombinant Antibody (V2-347930)
SKU: CBMAB-T0001-YJ
Rating: 5 (1 reviews)

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Datasheet

Summary

Host Animal

Mouse

Specificity

Human

Clone

V2-347930

Antibody Isotype

IgG1

Application

WB, IP, IF, ELISA

Basic Information

Immunogen

Raised against amino acids 786-900 mapping within an internal region of TARSH of human origin

Specificity

Human

Antibody Isotype

IgG1

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Application	Note
WB	1:100-1:1,000
IP	1-2 µg per 100-500 µg of total protein (1 ml of cell lysate)
IF(ICC)	1:50-1:500
ELISA	1:30-1:3,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer

PBS, 0.1% gelatin

Preservative

< 0.1% sodium azide

Concentration

0.2 mg/ml

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name

ABI family, member 3 (NESH) binding protein

Introduction

ABI3BP functions in extracellular matrix organization, positive regulation of cell-substrate adhesion.

Entrez Gene ID

25890

UniProt ID

Q7Z7G0

Alternative Names

TARSH; NESHBP

Cellular Location

Secreted

Involvement in disease

Defects in ABI3BP has been found in a patient with isolated coloboma, a defect of the eye characterized by the absence of ocular structures due to abnormal morphogenesis of the optic cup and stalk, and the fusion of the fetal fissure (optic fissure). Isolated colobomas may be associated with an abnormally small eye (microphthalmia) or small cornea.

More Infomation

References

Cai, H., Li, Y., Qin, D., Wang, R., Tang, Z., Lu, T., & Cui, Y. (2020). The Depletion of ABI3BP by MicroRNA-183 Promotes the Development of Esophageal Carcinoma. Mediators of Inflammation, 2020.

Lin, N., Yao, Z., Xu, M., Chen, J., Lu, Y., Yuan, L., ... & Xu, R. (2019). Long noncoding RNA MALAT1 potentiates growth and inhibits senescence by antagonizing ABI3BP in gallbladder cancer cells. Journal of Experimental & Clinical Cancer Research, 38(1), 1-15.

Delfín, D. A., DeAguero, J. L., & McKown, E. N. (2019). The extracellular matrix protein ABI3BP in cardiovascular health and disease. Frontiers in cardiovascular medicine, 6, 23.

Kimbrel, N. A., Garrett, M. E., Dennis, M. F., Research, V. M. A. M. I., Hauser, M. A., Ashley-Koch, A. E., & Beckham, J. C. (2018). A genome-wide association study of suicide attempts and suicidal ideation in US military veterans. Psychiatry research, 269, 64-69.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Associated Products

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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Documents

Datasheet
SDS
Request for COA

Request bulk or custom quote Online Inquiry
Second antibody and isotype control

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