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Mouse Anti-EPB41L1 Recombinant Antibody (2D10) (CBMAB-A2633-LY)

The product is antibody recognizes EPB41L1. The antibody 2D10 immunoassay techniques such as: WB, ELISA.
See all EPB41L1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
2D10
Antibody Isotype
IgG2a, κ
Application
WB, ELISA

Basic Information

Immunogen
EPB41L1 (NP_818932, 1 a.a. ~ 88 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
erythrocyte membrane protein band 4.1-like 1
Introduction
Erythrocyte membrane protein band 4.1 (EPB41) is a multifunctional protein that mediates interactions between the erythrocyte cytoskeleton and the overlying plasma membrane. The protein encoded by this gene is a neuronally-enriched protein that is structurally similar to EPB41. The encoded protein binds and stabilizes D2 and D3 dopamine receptors at the neuronal plasma membrane. Multiple transcript variants encoding different isoforms have been found for this gene, but the full-length nature of only two of them has been determined. [provided by RefSeq]
Entrez Gene ID
2036
UniProt ID
Q9H4G0
Alternative Names
4.1N; DKFZp686H17242; KIAA0338; MGC11072
Research Area
May function to confer stability and plasticity to neuronal membrane via multiple interactions, including the spectrin-actin-based cytoskeleton, integral membrane channels and membrane-associated guanylate kinases.
Biological Process
Actomyosin structure organization Source: GO_Central
Cortical actin cytoskeleton organization Source: InterPro
Cellular Location
Cytoskeleton
Involvement in disease
Mental retardation, autosomal dominant 11 (MRD11):
A disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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