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Mouse Anti-EPHA6 (AA 613-712) Recombinant Antibody (CBFYE-0236) (CBMAB-E0488-FY)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYE-0236
Antibody Isotype
IgG1
Application
ELISA, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Concentration
0.5 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
AA 613-712

Target

Full Name
EPH Receptor A6
Introduction
EPHA6 (EPH Receptor A6) is a Protein Coding gene. Diseases associated with EPHA6 include Oculoauricular Syndrome. Among its related pathways are Development Slit-Robo signaling and EPH-Ephrin signaling. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is EPHA3.
Entrez Gene ID
285220
UniProt ID
Q9UF33
Alternative Names
EPH Receptor A6; EPH Homology Kinase 2; EPH-Like Kinase 12; EC 2.7.10.1; EHK-2; HEK12; EHK2
Research Area
Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling (By similarity).
Biological Process
Axon guidance Source: GO_Central
Positive regulation of kinase activity Source: GO_Central
Transmembrane receptor protein tyrosine kinase signaling pathway Source: GO_Central
Cellular Location
Membrane
Topology
Extracellular: 23-550
Helical: 551-571
Cytoplasmic: 572-1036
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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