Recombinant Mouse Anti-EPN3 Recombinant Antibody (VA45-6-2) (CBMAB-XB0402-YC)

Name: Recombinant Mouse Anti-EPN3 Recombinant Antibody (VA45-6-2)
SKU: CBMAB-XB0402-YC
Rating: 5 (1 reviews)

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Datasheet

Summary

Host Animal

Mouse

Specificity

Human, Mouse

Clone

VA45-6-2

Application

IHC, IF, IP, WB

Basic Information

Specificity

Human, Mouse

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name

Epsin 3

Introduction

EPN3 (Epsin 3) is a protein coding gene. Among its related pathways are PAK Pathway and Endocytic Trafficking of EGFR. Gene Ontology annotations related to this gene include lipid binding and EH domain binding. An important paralog of this gene is EPN2.

Entrez Gene ID

Human	55040
Mouse	71889

UniProt ID

Human	Q9H201
Mouse	Q91W69

Alternative Names

Epsin 3; EPS-15-Interacting Protein 3; Epsin-3;

Biological Process

Endocytosis Source: GO_Central

Cellular Location

Nucleus; Cytoplasm; Perinuclear region; Clathrin-coated vesicle. Concentrated in the perinuclear region and associated with clathrin-coated vesicles close to the cell periphery. May shuttle to the nucleus.

More Infomation

References

Wu, Q., Li, Q., Zhu, W., Zhang, X., & Li, H. (2022). Epsin 3 potentiates the NF‑κB signaling pathway to regulate apoptosis in breast cancer. Molecular Medicine Reports, 25(1), 1-10.

Wang, Y., Song, W., Kan, P., Huang, C., Ma, Z., Wu, Q., ... & Zhang, B. (2018). Overexpression of Epsin 3 enhances migration and invasion of glioma cells by inducing epithelial‑mesenchymal transition. Oncology Reports, 40(5), 3049-3059.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Associated Products

Related Products

Rabbit Anti-EPN3 Recombinant Antibody (EG1118)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Learn more

Documents

Datasheet
SDS
Request for COA

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Second antibody and isotype control

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