Mouse Anti-EVI2B Recombinant Antibody (MEM-216) (CBMAB-E0345-FY)

Name: Mouse Anti-EVI2B Recombinant Antibody (MEM-216)
SKU: CBMAB-E0345-FY
Rating: 5 (1 reviews)

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Datasheet

Summary

Host Animal

Mouse

Specificity

Human

Clone

MEM-216

Antibody Isotype

IgG1

Application

IP, FC

Basic Information

Immunogen

Raji cells

Specificity

Human

Antibody Isotype

IgG1

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Concentration

1 mg/mL

Purity

>95% by SDS-PAGE

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name

ecotropic viral integration site 2B

Introduction

EVI2B (Ecotropic Viral Integration Site 2B) is a Protein Coding gene.

Entrez Gene ID

2124

UniProt ID

P34910

Alternative Names

Ecotropic Viral Integration Site 2B; Ecotropic Viral Integration Site 2B Protein Homolog; EVI-2B; EVDB; Protein EVI2B; CD361 Antigen; D17S376; CD361

Research Area

Required for granulocyte differentiation and functionality of hematopoietic progenitor cells through the control of cell cycle progression and survival of hematopoietic progenitor cells.

Biological Process

Myeloid cell development Source: UniProtKB
Negative regulation of apoptotic process Source: UniProtKB
Positive regulation of granulocyte differentiation Source: UniProtKB
Positive regulation of neutrophil differentiation Source: UniProtKB
Regulation of cell cycle Source: UniProtKB
Regulation of stem cell division Source: UniProtKB

Cellular Location

Membrane

Topology

Extracellular: 22-202
Helical: 203-226
Cytoplasmic: 227-448

More Infomation

References

Yonekura, S., & Ueda, K. (2021). EVI2B Is a New Prognostic Biomarker in Metastatic Melanoma with IFNgamma Associated Immune Infiltration. Cancers, 13(16), 4110.

Zjablovskaja, P., Kardosova, M., Danek, P., Angelisova, P., Benoukraf, T., Wurm, A. A., ... & Alberich-Jorda, M. (2019). Correction to: EVI2B is a C/EBPα target gene required for granulocytic differentiation and functionality of hematopoietic progenitors. Cell Death and Differentiation, 26(1), 198.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Associated Products

Related Products

Mouse Anti-EVI2B (AA 23-122) Recombinant Antibody (CBFYE-1372)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Learn more

Documents

Datasheet
SDS
Request for COA

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Second antibody and isotype control

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