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Mouse Anti-EXOC2 Recombinant Antibody (CF156) (CBMAB-FT120LY)

The product is antibody recognizes EXOC2. The antibody CF156 immunoassay techniques such as: ELISA, WB, IF, IP.
See all EXOC2 antibodies

Summary

Host Animal
Mouse
Specificity
Human, Mouse
Clone
CF156
Antibody Isotype
IgG1
Application
ELISA, WB, IF, IP

Basic Information

Immunogen
exocyst complex component 2
Specificity
Human, Mouse
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
50% glycerol
Preservative
0.02% sodium azide
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Exocyst Complex Component 2
Introduction
The protein encoded by this gene is a component of the exocyst complex, a multi-protein complex essential for the polarized targeting of exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and the functions of the exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. This interaction has been shown to mediate filopodia formation in fibroblasts. This protein has been shown to interact with the Ral subfamily of GTPases and thereby mediate exocytosis by tethering vesicles to the plasma membrane. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]
Entrez Gene ID
Human55770
Mouse66482
UniProt ID
HumanQ96KP1
MouseQ9D4H1
Research Area
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Biological Process
Exocytosis Source: GO_Central
Golgi to plasma membrane transport Source: GO_Central
Protein transport Source: UniProtKB-KW
Regulation of entry of bacterium into host cell Source: AgBase
Cellular Location
Midbody ring. Recruitment to the midbody does not require RALA, nor RALB (PubMed:18756269). Colocalizes with CNTRL/centriolin at the midbody ring (PubMed:16213214).
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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