Rabbit Anti-FAM134C Recombinant Antibody (CBXF-1091) (CBMAB-F0789-CQ)

This product is a rabbit antibody that recognizes FAM134C. The antibody CBXF-1091 can be used for immunoassay techniques such as: WB.
See all FAM134C antibodies

Summary

Host Animal

Rabbit

Specificity

Human

Clone

CBXF-1091

Antibody Isotype

IgG

Application

Basic Information

Specificity

Human

Antibody Isotype

IgG

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name

Family with sequence similarity 134 member C

Introduction

FAM134C (Family With Sequence Similarity 134 Member C) is a Protein Coding gene. An important paralog of this gene is FAM134A.

Entrez Gene ID

162427

UniProt ID

Q86VR2

Alternative Names

Family With Sequence Similarity 134 Member C; Family With Sequence Similarity 134, Member C

Research Area

Mediates NRF1-enhanced neurite outgrowth.

Biological Process

Positive regulation of neuron projection development Source: UniProtKB
Reticulophagy Source: InterPro

Cellular Location

Membrane

References

Di Lorenzo, G., Iavarone, F., Maddaluno, M., Plata-Gómez, A. B., Aureli, S., Quezada Meza, C. P., ... & Settembre, C. (2022). Phosphorylation of FAM134C by CK2 controls starvation-induced ER-phagy. Science advances, 8(35), eabo1215.

Zhao, J., Li, Z., & Li, J. (2022). The crystal structure of the FAM134B–GABARAP complex provides mechanistic insights into the selective binding of FAM134 to the GABARAP subfamily. FEBS Open bio, 12(1), 320-331.

Di Lorenzo, G., Iavarone, F., Maddaluno, M., Grumati, P., & Settembre, C. (2022). RETREG3/FAM134C phosphorylation by CSNK2 regulates reticulophagy during starvation. Autophagy Reports, 1(1), 519-522.

Reggio, A., Buonomo, V., Berkane, R., Bhaskara, R. M., Tellechea, M., Peluso, I., ... & Stolz, A. (2021). Role of FAM134 paralogues in endoplasmic reticulum remodeling, ER‐phagy, and collagen quality control. EMBO reports, 22(9), e52289.

Kumar, D., Lak, B., Suntio, T., Vihinen, H., Belevich, I., Viita, T., ... & Jokitalo, E. (2021). RTN4B interacting protein FAM134C promotes ER membrane curvature and has a functional role in autophagy. Molecular Biology of the Cell, 32(12), 1158-1170.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Associated Products

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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Documents

Datasheet
SDS
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