Mouse Anti-FAM171A1 Recombinant Antibody (CBXF-2368) (CBMAB-F1135-CQ)

This product is a mouse antibody that recognizes FAM171A1. The antibody CBXF-2368 can be used for immunoassay techniques such as: FC.
See all FAM171A1 antibodies

Summary

Host Animal

Mouse

Specificity

Human

Clone

CBXF-2368

Antibody Isotype

IgG2a

Application

Basic Information

Specificity

Human

Antibody Isotype

IgG2a

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, 50% glycerol, pH 7.2

Concentration

1 mg/mL

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name

Family With Sequence Similarity 171 Member A1

Introduction

FAM171A1 (Family With Sequence Similarity 171 Member A1) is a Protein Coding gene. An important paralog of this gene is FAM171A2.

Entrez Gene ID

221061

UniProt ID

Q5VUB5

Alternative Names

Family With Sequence Similarity 171 Member A1; Astroprincin; C10orf38; Family With Sequence Similarity 171, Member A1; Chromosome 10 Open Reading Frame 38; Protein FAM171A1;

Research Area

Involved in the regulation of the cytoskeletal dynamics, plays a role in actin stress fiber formation.

Biological Process

Regulation of cell shape Source: UniProtKB
Stress fiber assembly Source: UniProtKB

Cellular Location

Cell membrane

Topology

Extracellular: 22-303
Helical: 304-324
Cytoplasmic: 325-890

References

Kaprio, T., Lindström, A. M., Rasila, T., Saavalainen, O., Beilmann-Lehtonen, I., Mustonen, H., ... & Andersson, L. C. (2021). Elevated tumor expression of Astroprincin (FAM171A1) is an independent marker of poor prognosis in colon cancer. BMC gastroenterology, 21(1), 1-8.

Wahab, A., Almangush, A., Andersson, L. C., Nieminen, P., & Salo, T. (2020). Impact of Astroprincin (FAM171A1) Expression in Oral Tongue Cancer. Frontiers in Oral Health, 1, 599421.

Sanawar, R., Mohan Dan, V., Santhoshkumar, T. R., Kumar, R., & Pillai, M. R. (2019). Estrogen receptor-α regulation of microRNA-590 targets FAM171A1—a modifier of breast cancer invasiveness. Oncogenesis, 8(1), 1-13.

Rasila, T., Saavalainen, O., Attalla, H., Lankila, P., Haglund, C., Hölttä, E., & Andersson, L. C. (2019). Astroprincin (FAM171A1, C10orf38): a regulator of human cell shape and invasive growth. The American Journal of Pathology, 189(1), 177-189.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Associated Products

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Datasheet
SDS
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Second antibody and isotype control

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