Mouse Anti-FGF22 Recombinant Antibody (CBXF-2158) (CBMAB-F1483-CQ)

This product is a mouse antibody that recognizes FGF22. The antibody CBXF-2158 can be used for immunoassay techniques such as: Neut, WB.
See all FGF22 antibodies

Datasheet

Summary

Host Animal

Mouse

Specificity

Human

Clone

CBXF-2158

Antibody Isotype

IgG2

Application

Neut, WB

Basic Information

Immunogen

Human recombinant FGF-22

Specificity

Human

Antibody Isotype

IgG2

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Lyophilized

Buffer

Lyophilized from a 0.2 μm filtered solution in PBS

Concentration

LYOPH

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name

Fibroblast Growth Factor 22

Introduction

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The mouse homolog of this gene was found to be preferentially expressed in the inner root sheath of the hair follicle, which suggested a role in hair development. Alternative splicing results in multiple transcript variants.

Entrez Gene ID

27006

UniProt ID

Q9HCT0

Alternative Names

Fibroblast Growth Factor 22; FGF-22;

Research Area

Plays a role in the fasting response, glucose homeostasis, lipolysis and lipogenesis. Can stimulate cell proliferation (in vitro). May be involved in hair development.

Biological Process

Animal organ morphogenesis Source: GO_Central
Cell differentiation Source: GO_Central
Fibroblast growth factor receptor signaling pathway Source: GO_Central
Positive regulation of cell population proliferation Source: GO_Central
Positive regulation of gene expression Source: GO_Central
Positive regulation of protein phosphorylation Source: GO_Central
Regulation of cell migration Source: GO_Central

Cellular Location

Secreted

References

Zhang, Z., Qin, Y., Ji, S., Xu, W., Liu, M., Hu, Q., ... & Xu, X. (2021). FGFBP1-mediated crosstalk between fibroblasts and pancreatic cancer cells via FGF22/FGFR2 promotes invasion and metastasis of pancreatic cancer. Acta Biochimica et Biophysica Sinica, 53(8), 997-1008.

Zhu, S., Chen, M., Chen, M., Ye, J., Ying, Y., Wu, Q., ... & Yu, K. (2020). Fibroblast growth factor 22 inhibits ER stress-induced apoptosis and improves recovery of spinal cord injury. Frontiers in Pharmacology, 11, 18.

Castilho, A. C. S., Dalanezi, F. M., Franchi, F. F., Price, C. A., Ferreira, J. C. P., Trevisol, E., & Buratini, J. (2019). expression of fibroblast growth factor 22 (FGF22) and Its receptor, FGFR1B, during development and regression of bovine corpus luteum. Theriogenology, 125, 1-5.

Liu, H. Y., Zhao, H., & Li, W. X. (2019). Integrated analysis of transcriptome and prognosis data identifies FGF22 as a prognostic marker of lung adenocarcinoma. Technology in cancer research & treatment, 18, 1533033819827317.

Yang, H., Tian, H., Cheng, J., Zheng, J., Wang, D., Sun, C., ... & Jiang, C. (2018). Highly efficient production of functional recombinant human fibroblast growth factor 22 in E. coli and its protective effects on H2O2-lesioned L02 cells. Protein Expression and Purification, 152, 114-121.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Associated Products

Related Products

Rabbit Anti-FGF22 Recombinant Antibody (EG1191)

Mouse Anti-FGF22 (AA 23-170) Recombinant Antibody (CBXF-2616)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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