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Mouse Anti-ALDOB Recombinant Antibody (19) (CBMAB-A2321-YC)

Provided herein is a Mouse monoclonal antibody against Human Aldolase, Fructose-Bisphosphate B. The antibody can be used for immunoassay techniques, such as FC, IHC, WB.
See all ALDOB antibodies

Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat
Clone
19
Antibody Isotype
IgG2a, κ
Application
WB, IP, ELISA

Basic Information

Immunogen
Full length recombinant protein of human ALDOB (NP_000026) produced in HEK293 cell.
Host Species
Mouse
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
WB1:100-1:1,000
IP1-2 µg per 100-500 µg of total protein (1 ml of cell lysate)
ELISA1:30-1:3,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, 0.1% gelatin
Preservative
< 0.1% sodium azide
Concentration
0.2 mg/ml
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Aldolase, Fructose-Bisphosphate B
Introduction
Fructose-1,6-bisphosphate aldolase (EC 4.1.2.13) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes whi
Entrez Gene ID
229
UniProt ID
P05062
Alternative Names
Aldolase, Fructose-Bisphosphate B; Aldolase B, Fructose-Bisphosphate; Liver-Type Aldolase; EC 4.1.2.13; ALDB; Aldolase B, Fructose-Bisphosphatase; Fructose-Bisphosphate Aldolase B; Aldolase 2; ALDO2;
Biological Process
Canonical glycolysis Source: Reactome
Fructose 1,6-bisphosphate metabolic process Source: BHF-UCL
Fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate Source: Reactome
Fructose metabolic process Source: BHF-UCL
Gluconeogenesis Source: Reactome
Glycolytic process Source: BHF-UCL
NADH oxidation Source: BHF-UCL
Positive regulation of ATPase activity Source: BHF-UCL
Vacuolar proton-transporting V-type ATPase complex assembly Source: BHF-UCL
Cellular Location
Centriolar satellite
Involvement in disease
Hereditary fructose intolerance (HFI): Autosomal recessive disease that results in an inability to metabolize fructose and related sugars. Complete exclusion of fructose results in dramatic recovery; however, if not treated properly, HFI subjects suffer episodes of hypoglycemia, general ill condition, and risk of death the remainder of life.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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