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Mouse Anti-CPLANE2 Recombinant Antibody (3G4) (CBMAB-A0955-LY)

Summary

Host Animal
Mouse
Specificity
Human
Clone
3G4
Antibody Isotype
IgG2a, κ
Application
WB, ELISA

Basic Information

Immunogen
C1orf89 (AAH02946.1, 1 a.a. ~ 258 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
CPLANE2
Entrez Gene ID
UniProt ID
Alternative Names
MGC10731; RP4-733M16.4
Function
Potential effector of the planar cell polarity signaling pathway. Plays a role in targeted membrane trafficking most probably at the level of vesicle fusion with membranes. Involved in cilium biogenesis by regulating the transport of cargo proteins to the basal body and to the apical tips of cilia. More generally involved in exocytosis in secretory cells (By similarity).
Biological Process
Cellular protein localization Source: UniProtKB
Cilium assembly Source: UniProtKB
Exocytosis Source: UniProtKB-KW
Protein transport Source: UniProtKB-KW
Regulation of exocytosis Source: UniProtKB
Regulation of vesicle fusion Source: UniProtKB
Cellular Location
Cilium basal body
More Infomation
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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