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Mouse Anti-CALB2 Recombinant Antibody (AF5D11) (CBMAB-C1238-CN)

This product is a Mouse antibody that recognizes CALB2. The antibody AF5D11 can be used for immunoassay techniques such as: WB.
See all CALB2 antibodies

Summary

Host Animal
Mouse
Specificity
Human, Mouse
Clone
AF5D11
Application
WB

Basic Information

Immunogen
Recombinant protein corresponding to human Calretinin(Calbindin2), expressed in E. coli
Specificity
Human, Mouse
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
HEPES, 0.15 M NaCl, 0.01% BSA, 50% glycerol
Preservative
0.03% Sodium azide

Target

Full Name
Calbindin 2
Introduction
This gene encodes an intracellular calcium-binding protein belonging to the troponin C superfamily. Members of this protein family have six EF-hand domains which bind calcium. This protein plays a role in diverse cellular functions, including message targeting and intracellular calcium buffering. It also functions as a modulator of neuronal excitability, and is a diagnostic marker for some human diseases, including Hirschsprung disease and some cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]
Entrez Gene ID
Human794
Mouse12308
UniProt ID
HumanP22676
MouseQ08331
Alternative Names
Calbindin 2; 29 KDa Calbindin; Calretinin; CAB29; CR; Testicular Secretory Protein Li 8;
Function
Calretinin is a calcium-binding protein which is abundant in auditory neurons.
Biological Process
Regulation of cytosolic calcium ion concentration Source: GO_Central
Regulation of long-term synaptic potentiation Source: GO_Central
Regulation of presynaptic cytosolic calcium ion concentration Source: GO_Central
Cellular Location
Cuticular plate; Cytosol; Nucleus; Synaptic membrane; Dendrite; Gap junction; Neuron projection; Parallel fiber to Purkinje cell synapse; Stereocilium; Synapse; Terminal bouton
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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