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Mouse Anti-CANP2 Recombinant Antibody (3G1) (CBMAB-C0376-YY)

This product is mouse antibody that recognizes CANP2. The antibody 3G1 can be used for immunoassay techniques such as: WB, IHC-P
See all CANP2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
3G1
Antibody Isotype
IgG2a
Application
WB, IHC-P

Basic Information

Specificity
Human
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Protein A purified
Concentration
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Calpain 2
Entrez Gene ID
824
UniProt ID
P17655
Alternative Names
Calcitonin Related Polypeptide Alpha; Calcitonin Gene-Related Peptide I; Alpha-Type CGRP; Calcitonin 1; Calcitonin; CGRP-I; CALC1; Calcitonin/Calcitonin-Related Polypeptide, Alpha;
Function
Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226' (PubMed:17650508).
Proteolytically cleaves CPEB3 following neuronal stimulation which abolishes CPEB3 translational repressor activity, leading to translation of CPEB3 target mRNAs (By similarity).
Biological Process
Behavioral response to pain Source: Ensembl
Blastocyst development Source: Ensembl
Cellular response to amino acid stimulus Source: UniProtKB
Cellular response to interferon-beta Source: Ensembl
Cellular response to lipopolysaccharide Source: Ensembl
Extracellular matrix disassembly Source: Reactome
Female pregnancy Source: Ensembl
Myoblast fusion Source: Ensembl
Positive regulation of cardiac muscle cell apoptotic process Source: Ensembl
Positive regulation of myoblast fusion Source: Ensembl
Positive regulation of neuron death Source: Ensembl
Positive regulation of phosphatidylcholine biosynthetic process Source: Ensembl
Protein autoprocessing Source: Ensembl
Proteolysis Source: UniProtKB
Proteolysis involved in cellular protein catabolic process Source: BHF-UCL
Regulation of cytoskeleton organization Source: BHF-UCL
Regulation of interleukin-6 production Source: Ensembl
Response to hydrogen peroxide Source: Ensembl
Response to hypoxia Source: Ensembl
Cellular Location
Cytoplasm; Cell membrane. Translocates to the plasma membrane upon Ca2+ binding.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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