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Rabbit Anti-CAR12 Recombinant Antibody (CBFYC-0808) (CBMAB-C0863-FY)

This product is rabbit antibody that recognizes CAR12. The antibody CBFYC-0808 can be used for immunoassay techniques such as: ELISA, WB.
See all CAR12 antibodies

Summary

Host Animal
Rabbit
Specificity
Mouse
Clone
CBFYC-0808
Antibody Isotype
IgG
Application
ELISA, WB

Basic Information

Immunogen
Recombinant Mouse Carbonic Anhydrase XIICA12 Protein
Specificity
Mouse
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, 5% trehalose
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
CARBONIC ANHYDRASE 12
Introduction
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. This gene product is a type I membrane protein that is highly expressed in normal tissues, such as kidney, colon and pancreas, and has been found to be overexpressed in 10% of clear cell renal carcinomas. Three transcript variants encoding different isoforms have been identified for this gene.CA12 (Carbonic Anhydrase 12) is a Protein Coding gene. Diseases associated with CA12 include Hyperchlorhidrosis, Isolated and Degenerative Disc Disease. Among its related pathways are Nitrogen metabolism and Metabolism. Gene Ontology (GO) annotations related to this gene include carbonate dehydratase activity. An important paralog of this gene is CA14.Reversible hydration of carbon dioxide.
Entrez Gene ID
76459
UniProt ID
Q8CI85
Alternative Names
Ca12; CA-XII; AI314958; 2310047E01Rik
Function
Reversible hydration of carbon dioxide.
Cellular Location
Integral component of membrane
Topology
Helical: 294-317 aa
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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