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Mouse Anti-CARD17 (AA 1-110) Recombinant Antibody (CBFYC-0812) (CBMAB-C0867-FY)

This product is mouse antibody that recognizes CARD17. The antibody CBFYC-0812 can be used for immunoassay techniques such as: ELISA, WB.
See all CARD17 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYC-0812
Antibody Isotype
IgG2a, k
Application
ELISA, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG2a, k
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
AA 1-110

Target

Full Name
caspase recruitment domain family member 17
Introduction
CARD17 (Caspase Recruitment Domain Family Member 17) is a Protein Coding gene. Among its related pathways are Toll-like receptor signaling pathway. Gene Ontology (GO) annotations related to this gene include cysteine-type endopeptidase inhibitor activity. An important paralog of this gene is CARD16.
Entrez Gene ID
440068
UniProt ID
Q5XLA6
Alternative Names
Caspase Recruitment Domain Family Member 17; Inhibitory Caspase Recruitment Domain Protein; Caspase-1 Inhibitor INCA; Inhibitory CARD; INCA; Inhibitory Caspase Recruitment Domain (CARD) Protein; Caspase Recruitment Domain-Containing Protein 17; Caspase Recruitment Domain Family, Member 17
Function
Regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-IL-1beta/IL1B and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. However, unlike CASP1, do not induce NF-kappa-B activation.
Biological Process
Cellular response to lipopolysaccharide Source: UniProtKB
Negative regulation of interleukin-1 beta production Source: UniProtKB
Regulation of apoptotic process Source: InterPro
Cellular Location
Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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