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Rabbit Anti-CBLN4 Recombinant Antibody (EG497) (CBMAB-EN564-LY)

The product is antibody recognizes CBLN4 . The antibody EG497 immunoassay techniques such as: WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:40000.
See all CBLN4 antibodies

Summary

Host Animal
Rabbit
Specificity
Human, Mouse
Clone
EG497
Antibody Isotype
IgG
Application
WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:40000

Basic Information

Immunogen
The antibody was produced against synthesized peptide derived from internal of human CBLN4.
Specificity
Human, Mouse
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Cerebellin 4 Precursor
Introduction
This gene encodes a member of a family of small secreted proteins containing C1Q domains. Members of this family are involved in regulation of neurexin signalling during synapse development. The mouse homolog of the protein encoded by this gene competes with netrin to bind to the deleted in colorectal cancer receptor. [provided by RefSeq, Aug 2012]
Entrez Gene ID
Human140689
Mouse228942
UniProt ID
HumanQ9NTU7
MouseQ8BME9
Alternative Names
Cerebellin 4 Precursor; Cerebellin-Like Glycoprotein 1; Cerebellin Precursor-Like 1; CBLNL1; Cerebellin-4;
Function
Acts as a synaptic organizer in specific subsets of neurons in the brain (By similarity).
Essential for the formation and maintenance of inhibitory GABAergic synapses (By similarity).
Promotes the development of dendrite-targeting inhibitory GABAergic synapses made by somatostatin-positive interneurons (By similarity).
May contribute to the function of ventral medial habenula region of the brain implicated in the regulation of anxiety-related behaviors (By similarity).
May play a role in CBLN3 export from the endoplasmic reticulum and secretion (By similarity).
Biological Process
Inhibitory synapse assembly Source: UniProtKB
Protein secretion Source: Ensembl
Cellular Location
Secreted; Synapse. Detected at GABAergic synapses.
PTM
Sialoglycoprotein.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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