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Mouse Anti-CCNE2 Recombinant Antibody (CBCNC-155) (CBMAB-C1468-CN)

This product is a Mouse antibody that recognizes CCNE2. The antibody CBCNC-155 can be used for immunoassay techniques such as: WB, IHC, IF.
See all CCNE2 antibodies

Summary

Host Animal
Mouse
Specificity
Human, Mouse
Clone
CBCNC-155
Antibody Isotype
IgG1
Application
WB, IHC, IF

Basic Information

Immunogen
A synthetic peptide (conjugated with KLH) corresponding to the C-terminal of Cyclin E2
Specificity
Human, Mouse
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
TBS, pH 7.4, 0.5% BSA, 25% glycerol
Preservative
0.05% Sodium azide

Target

Full Name
Cyclin E2
Introduction
CCNE2 (Cyclin E2) is a Protein Coding gene. Among its related pathways are CDK-mediated phosphorylation and removal of Cdc6 and Cyclins and Cell Cycle Regulation. Gene Ontology (GO) annotations related to this gene include protein kinase binding and cyclin-dependent protein serine/threonine kinase regulator activity. An important paralog of this gene is CCNE1.
Entrez Gene ID
Human9134
Mouse12448
UniProt ID
HumanO96020
MouseQ9Z238
Alternative Names
Cyclin E2; G1/S-Specific Cyclin-E2; CYCE2;
Function
Essential for the control of the cell cycle at the late G1 and early S phase.
Biological Process
Cell division Source: UniProtKB-KW
DNA replication initiation Source: Ensembl
G1/S transition of mitotic cell cycle Source: GO_Central
Homologous chromosome pairing at meiosis Source: Ensembl
Mitotic cell cycle phase transition Source: GO_Central
Regulation of cellular protein localization Source: Ensembl
Regulation of cyclin-dependent protein serine/threonine kinase activity Source: GO_Central
Telomere maintenance Source: Ensembl
Cellular Location
Nucleus
PTM
Phosphorylation by CDK2 triggers its release from CDK2 and degradation via the ubiquitin proteasome pathway.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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