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Mouse Anti-CD4 Recombinant Antibody (10B1533) (CBMAB-C1729-CN)

This product is a Mouse antibody that recognizes CD4. The antibody 10B1533 can be used for immunoassay techniques such as: FC.
See all CD4 antibodies

Summary

Host Animal
Mouse
Specificity
Goat, Sheep
Clone
10B1533
Antibody Isotype
IgG2a
Application
FC

Basic Information

Immunogen
Fetal thymocytes
Specificity
Goat, Sheep
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Lyophilized
Buffer
PBS, pH 7.4, 1% BSA, 5% sucrose. Reconstitute with 1 mL sterile ddH2O
Preservative
0.09% Sodium azide

Target

Full Name
CD4 Molecule
Introduction
CD4 (CD4 Molecule) is a Protein Coding gene. Diseases associated with CD4 include Okt4 Epitope Deficiency and Pilonidal Sinus. Among its related pathways are G-protein signaling N-RAS regulation pathway and PEDF Induced Signaling. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and enzyme binding.
Entrez Gene ID
Goat102170124
Sheep443509
UniProt ID
GoatA0A452E3R1
SheepQ19VJ6
Alternative Names
CD4 Molecule; T-Cell Surface Glycoprotein CD4; T-Cell Surface Antigen T4/Leu-3; CD4 Antigen (P55); CD4 Receptor; CD4 Antigen; CD4mut;

Xing, J., Luo, K., Tang, X., & Zhan, W. (2019). Influence of CD4-1+, CD4-2+ and CD8+ T lymphocytes subpopulations on the immune response of B lymphocytes in flounder (Paralichthys olivaceus) immunized with thymus-dependent or thymus-independent antigen. Fish & shellfish immunology, 84, 979-986.

Taniuchi, I. (2018). CD4 helper and CD8 cytotoxic T cell differentiation. Annual review of immunology, 36, 579-601.

Dhanda, S. K., Karosiene, E., Edwards, L., Grifoni, A., Paul, S., Andreatta, M., ... & Sette, A. (2018). Predicting HLA CD4 immunogenicity in human populations. Frontiers in Immunology, 9, 1369.

Prasad, S., Neef, T., Xu, D., Podojil, J. R., Getts, D. R., Shea, L. D., & Miller, S. D. (2018). Tolerogenic Ag-PLG nanoparticles induce tregs to suppress activated diabetogenic CD4 and CD8 T cells. Journal of autoimmunity, 89, 112-124.

Sun, G., Sun, X., Li, W., Liu, K., Tian, D., Dong, Y., ... & Zhang, D. (2018). Critical role of OX40 in the expansion and survival of CD4 T-cell-derived double-negative T cells. Cell death & disease, 9(6), 1-13.

Liu, Q., Acharya, P., Dolan, M. A., Zhang, P., Guzzo, C., Lu, J., ... & Lusso, P. (2017). Quaternary contact in the initial interaction of CD4 with the HIV-1 envelope trimer. Nature structural & molecular biology, 24(4), 370-378.

Michels, A. W., Landry, L. G., McDaniel, K. A., Yu, L., Campbell-Thompson, M., Kwok, W. W., ... & Nakayama, M. (2017). Islet-derived CD4 T cells targeting proinsulin in human autoimmune diabetes. Diabetes, 66(3), 722-734.

Hamze, M., Meunier, S., Karle, A., Gdoura, A., Goudet, A., Szely, N., ... & Maillère, B. (2017). Characterization of CD4 T cell epitopes of infliximab and rituximab identified from healthy donors. Frontiers in immunology, 8, 500.

Takeuchi, A., & Saito, T. (2017). CD4 CTL, a cytotoxic subset of CD4+ T cells, their differentiation and function. Frontiers in immunology, 8, 194.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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