Mouse Anti-CENTG2 / AGAP1 Recombinant Antibody (CBYY-C1874) (CBMAB-C3312-YY)

This product is mouse antibody that recognizes CENTG2 / AGAP1. The antibody CBYY-C1874 can be used for immunoassay techniques such as: FC, IHC-P, WB
See all CENTG2 / AGAP1 antibodies

Summary

Host Animal

Mouse

Specificity

Human

Clone

CBYY-C1874

Antibody Isotype

IgG1

Application

FC, IHC-P, WB

Basic Information

Specificity

Human

Antibody Isotype

IgG1

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Protein A/G purified

Buffer

0.5 mg/mL

Preservative

50% glycerol, 1% BSA, PBS, pH 7.3

Concentration

Liquid

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name

ArfGAP with GTPase domain, ankyrin repeat and PH domain 1

Entrez Gene ID

116987

UniProt ID

Q9UPQ3

Function

GTPase-activating protein for ARF1 and, to a lesser extent, ARF5. Directly and specifically regulates the adapter protein 3 (AP-3)-dependent trafficking of proteins in the endosomal-lysosomal system.

Biological Process

Protein transport

Cellular Location

Cytoplasm. Associates with the endocytic compartment.

PTM

Phosphorylated on tyrosines.

References

Tsutsumi, K., Nakamura, Y., Kitagawa, Y., Suzuki, Y., Shibagaki, Y., Hattori, S., & Ohta, Y. (2020). AGAP1 regulates subcellular localization of FilGAP and control cancer cell invasion. Biochemical and biophysical research communications, 522(3), 676-683.

Pacault, M., Nizon, M., Pichon, O., Vincent, M., Le Caignec, C., & Isidor, B. (2019). A de novo 2q37. 2 deletion encompassing AGAP1 and SH3BP4 in a patient with autism and intellectual disability. European journal of medical genetics, 62(12), 103586.

Roy, N. S., Luo, R., & Randazzo, P. A. (2017). Phosphoinositides and Kinesin 13 Family Member Kif2A Cooperatively Regulate Arf GTPase Activating Protein AGAP1. The FASEB Journal, 31, 765-7.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Associated Products

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Datasheet
SDS
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Second antibody and isotype control

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