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Rat Anti-CHIL3 Recombinant Antibody (7C3) (CBMAB-C8593-LY)

This product is antibody recognizes CHIL3. The antibody 7C3 immunoassay techniques such as: ELISA.
See all CHIL3 antibodies

Summary

Host Animal
Rat
Specificity
Mouse
Clone
7C3
Antibody Isotype
IgG2a
Application
ELISA

Basic Information

Specificity
Mouse
Antibody Isotype
IgG2a
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Lyophilized
Buffer
5% trehalose
Concentration
0.5 mg/ml
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
chitinase-like 3
Entrez Gene ID
12655
UniProt ID
O35744
Function
Lectin that binds saccharides with a free amino group, such as glucosamine or galactosamine. Binding to oligomeric saccharides is much stronger than binding to mono- or disaccharides. Also binds chitin and heparin. Has weak hexosaminidase activity but no chitinase activity. Has chemotactic activity for T-lymphocytes, bone marrow cells and eosinophils. May play a role in inflammation and allergy.
Biological Process
Chitin catabolic process Source: GO_Central
Inflammatory response Source: MGI
Polysaccharide catabolic process Source: UniProtKB-KW
Cellular Location
Rough endoplasmic reticulum lumen; Secreted; Nucleus envelope; Cytoplasm; Cytoplasmic granule. Predominantly localizes to the lumen of rough endoplasmic reticulum (rER) and nuclear envelope in alveolar macrophages. Localizes to the dilated lumen of rER in immature neutrophils in spleen and in cytoplasmic granules in peritoneal neutrophils. Detected in needle-shaped crystals present in the cytoplasm of bone marrow macrophages.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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