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Rabbit Anti-CLCC1 Recombinant Antibody (EG715) (CBMAB-EN869-LY)

The product is antibody recognizes CLCC1. The antibody EG715 immunoassay techniques such as: WB: 1:500~1:1000 IF: 1:100~1:500 ELISA: 1:40000.
See all CLCC1 antibodies

Summary

Host Animal
Rabbit
Specificity
Human
Clone
EG715
Antibody Isotype
IgG
Application
WB: 1:500~1:1000 IF: 1:100~1:500 ELISA: 1:40000

Basic Information

Immunogen
The antibody was produced against synthesized peptide derived from internal of human CLCC1.
Specificity
Human
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Chloride Channel CLIC Like 1
Introduction
CLCC1 (Chloride Channel CLIC Like 1) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include chloride channel activity.
Entrez Gene ID
23155
UniProt ID
Q96S66
Alternative Names
Chloride Channel CLIC Like 1; Mid-1-Related Chloride Channel Protein 1; MCLC; Mid1-Related Chloride Channel (Yeast); Chloride Channel CLIC-Like Protein 1; Chloride Channel CLIC-Like 1; KIAA0761;
Function
Seems to act as a chloride ion channel (PubMed:30157172).

Plays a role in retina development (PubMed:30157172).
Biological Process
Chloride transport Source: UniProtKB-KW
Cellular Location
Endoplasmic reticulum membrane; Nucleus membrane; Golgi apparatus membrane. Within the endoplasmic reticulum (ER), localizes to the mitochondria-associated ER membrane, a zone of contact between the ER and mitochondrial membranes.
Involvement in disease
Retinitis pigmentosa 32 (RP32):
A form of retinitis pigmentosa, a retinal dystrophy belonging to the group of pigmentary retinopathies. Retinitis pigmentosa is characterized by retinal pigment deposits visible on fundus examination and primary loss of rod photoreceptor cells followed by secondary loss of cone photoreceptors. Patients typically have night vision blindness and loss of midperipheral visual field. RP32 inheritance is autosomal recessive.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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