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Mouse Anti-CLEC2A Recombinant Antibody (705518) (CBMAB-C8410-LY)

This product is antibody recognizes CLEC2A. The antibody 705518 immunoassay techniques such as: FC, CyTOF.
See all CLEC2A antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
705518
Antibody Isotype
IgG1
Application
FC, CyTOF

Basic Information

Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Concentration
0.2 mg/ml
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
C-Type Lectin Domain Family 2 Member A
Introduction
CLEC2A belongs to the CLEC2 family of activation-induced, natural killer gene complex-encoded C-type lectin-like receptors (Spreu et al., 2007 [PubMed 18046548]).[supplied by OMIM, May 2008]
Entrez Gene ID
387836
UniProt ID
Q6UVW9
Alternative Names
C-Type Lectin Domain Family 2 Member A; Proliferation-Induced Lymphocyte-Associated Receptor; Keratinocyte-Associated C-Type Lectin; PILAR; KACL; C-Type Lectin Domain Family 2, Member A; INPE5792; UNQ5792;
Function
Plays a role in modulating the extent of T-cell expansion. Enhances the expansion of TCR-stimulated T-cells by increasing their survival through enhanced expression of anti-apoptotic proteins. May modulate the capacity of T-cells to home to lymph nodes through SELL. Facilitates dedicated immune recognition of keratinocytes via interaction with its receptor KLRF2 by stimulating natural killer cell mediated cytotoxicity.
Biological Process
Natural killer cell mediated cytotoxicity Source: UniProtKB
Cellular Location
Cell membrane
Topology
Cytoplasmic: 1-27
Helical: 28-48
Extracellular: 49-174
PTM
N-glycosylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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