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Mouse Anti-CLEC3B Recombinant Antibody (CBYJT-1128) (CBMAB-T0140-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to CLEC3B (C-Type Lectin Domain Family 3 Member B). The antibody can be used for immunoassay techniques, such as ELISA, WB, IHC.
See all CLEC3B antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-1128
Antibody Isotype
IgG2a, κ
Application
ELISA, WB, IHC

Basic Information

Immunogen
Recognizes aa17-181 of human tetranectin monomer. Epitope specificity is shared with clone 6F193, as determined by inhibition ELISA. Reacts poorly with tetranectin (TN) in sandwich ELISA in combination with a Pab against tetranectin. In Western Blot reacts strongly with TN monomer. Especially good as detecting antibody in combination with clone 6F216 in sandwich ELISA. Strong recognition of tetranectin in immunohistochemistry on both fresh frozen and paraffin-embedded tissues
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.2, 40% Glycerol
Preservative
15 mM Sodium Azide
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 17-181

Target

Full Name
C-Type Lectin Domain Family 3 Member B
Introduction
CLEC3B (C-Type Lectin Domain Family 3 Member B) is a Protein Coding gene. Diseases related to CLEC3B include Ovarian Cancer. Among its related pathways are Response to elevated platelet cytosolic Ca2+. Gene Ontology (GO) annotations related to CLEC3B include calcium ion binding and heparin binding. An important paralog of CLEC3B is CLEC3A.
Entrez Gene ID
7123
UniProt ID
P05452
Alternative Names
C-Type Lectin Domain Family 3 Member B; Plasminogen Kringle 4-Binding Protein; TNA; TN; Tetranectin (Plasminogen Binding Protein); Tetranectin (Plasminogen-Binding Protein); C-Type Lectin Domain Family 3, Member B; Tetranectin
Function
Tetranectin binds to plasminogen and to isolated kringle 4. May be involved in the packaging of molecules destined for exocytosis.
Biological Process
Bone mineralization Source: UniProtKB
Cellular response to organic substance Source: UniProtKB
Cellular response to transforming growth factor beta stimulus Source: UniProtKB
Ossification Source: UniProtKB
Platelet degranulation Source: Reactome
Positive regulation of plasminogen activation Source: UniProtKB
Cellular Location
Secreted
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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