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Mouse Anti-CLIP2 Recombinant Antibody (CBYY-C2981) (CBMAB-C4424-YY)

This product is mouse antibody that recognizes CLIP2. The antibody CBYY-C2981 can be used for immunoassay techniques such as: ELISA, WB
See all CLIP2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYY-C2981
Antibody Isotype
IgG2a, κ
Application
ELISA, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Protein A purified
Preservative
PBS, pH 7.2
Concentration
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
CAP-Gly Domain Containing Linker Protein 2
Entrez Gene ID
7461
UniProt ID
Q9UDT6
Alternative Names
CCR4-NOT Transcription Complex Subunit 6; Carbon Catabolite Repressor Protein 4 Homolog; Cytoplasmic Deadenylase; EC 3.1.13.4; Ccr4a; CCR4;
Function
Seems to link microtubules to dendritic lamellar body (DLB), a membranous organelle predominantly present in bulbous dendritic appendages of neurons linked by dendrodendritic gap junctions. May operate in the control of brain-specific organelle translocations (By similarity).
Biological Process
Cytoplasmic microtubule organization Source: GO_Central
Cellular Location
Cytoskeleton; Cytoplasm. Localizes preferentially to the ends of tyrosinated microtubules.
Involvement in disease
CLIP2 is located in the Williams-Beuren syndrome (WBS) critical region (PubMed:9799601). WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region. Haploinsufficiency of CLIP2 may be the cause of certain cardiovascular and musculo-skeletal abnormalities observed in the disease. However, it has been demonstrated that haploinsufficiency of this gene alone is not sufficient to cause any of the cognitive or facial features of WBS (PubMed:22608712).
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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