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Mouse Anti-CLTCL1 Recombinant Antibody (55) (CBMAB-AP1552LY)

Summary

Host Animal
Mouse
Specificity
Human
Clone
55
Antibody Isotype
IgG2a
Application
ELISA, IF, IHC, WB

Basic Information

Immunogen
Synthetic Peptide
Specificity
Human
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Clathrin Heavy Chain Like 1
Introduction
This gene is a member of the clathrin heavy chain family and encodes a major protein of the polyhedral coat of coated pits and vesicles. Chromosomal aberrations involving this gene are associated with meningioma, DiGeorge syndrome, and velo-cardio-facial syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009]
Entrez Gene ID
UniProt ID
Alternative Names
Clathrin Heavy Chain Like 1; Clathrin Heavy Chain On Chromosome 22; Clathrin, Heavy Polypeptide-Like 1; CLH-22; CLTCL; CLH22;
Function
Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Two different adapter protein complexes link the clathrin lattice either to the plasma membrane or to the trans-Golgi network (By similarity).
Biological Process
Anatomical structure morphogenesis Source: ProtInc
Intracellular protein transport Source: InterPro
Membrane organization Source: Reactome
Mitotic cell cycle Source: UniProtKB
Positive regulation of glucose import Source: UniProtKB
Receptor-mediated endocytosis Source: UniProtKB
Retrograde transport, endosome to Golgi Source: UniProtKB
Cellular Location
Cytoplasmic vesicle membrane; Coated pit. Cytoplasmic face of coated pits and vesicles.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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