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Mouse Anti-CNTLN (AA 971-1070) Recombinant Antibody (CBFYC-2015) (CBMAB-C2081-FY)

This product is mouse antibody that recognizes CNTLN. The antibody CBFYC-2015 can be used for immunoassay techniques such as: ELISA, WB.
See all CNTLN antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYC-2015
Antibody Isotype
IgG2a, k
Application
ELISA, WB

Basic Information

Immunogen
CNTLN (NP_060208, 971 a.a.-1070 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Immunogen sequence: QNDVHVVRRQ IRELKKMKKN RDACKTSTHK AQTLAASILN ISRSDLEEIL DTEDQVEIEK TKIDAENDKE WMLYIQKLLE GQSLALSPRL KCNGAIMAHQ
Specificity
Human
Antibody Isotype
IgG2a, k
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
AA 971-1070

Target

Full Name
centlein, centrosomal protein
Introduction
CNTLN (Centlein) is a Protein Coding gene. Diseases associated with CNTLN include Microcephalic Osteodysplastic Primordial Dwarfism, Type Ii and Corneal Dystrophy, Meesmann. Gene Ontology (GO) annotations related to this gene include protein kinase binding and protein binding, bridging.
Entrez Gene ID
54875
UniProt ID
Q9NXG0
Alternative Names
Centlein; Centlein, Centrosomal Protein; Centrosomal Protein; C9orf101; C9orf39; Chromosome 9 Open Reading Frame 101; Chromosome 9 Open Reading Frame 39; BA340N12.1
Function
Required for centrosome cohesion and recruitment of CEP68 to centrosomes.
Biological Process
Centriole-centriole cohesion Source: UniProtKB
Protein localization to organelle Source: UniProtKB
Cellular Location
Centriole. Colocalizes with gamma-tubulin during interphase and mitosis. Appears to associate with the mother centriole during G1 phase and with daughter centrioles towards G1/S phase (By similarity). Localizes to the proximal ends of the centrioles (PubMed:24554434). Levels are high at interphase centrosomes but are reduced on mitotic spindle poles (PubMed:24554434).
PTM
Phosphorylated directly or indirectly by NEK2.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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