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Recombinant Mouse Anti-CNTROB Recombinant Antibody (6D4F4) (CBMAB-XB0269-YC)

Provided herein is a Mouse Recombinant Antibody against Centrobin, Centriole Duplication And Spindle Assembly Protein. The antibody can be used for immunoassay techniques, such as IHC, IF, IP, WB.
See all CNTROB antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
6D4F4
Antibody Isotype
IgG1, κ
Application
IHC, IF, IP, WB

Basic Information

Immunogen
Recombinant human centrobin amino acids 113-361 (bacterially expressed from pGEX4T as a GST fusion, then thrombin-cleaved and purified).
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Centrobin, Centriole Duplication And Spindle Assembly Protein
Introduction
CNTROB (Centrobin, Centriole Duplication And Spindle Assembly Protein) is a protein coding gene. Diseases associated with CNTROB include Squamous Cell Papilloma and Salivary Gland Disease. Gene Ontology annotations related to this gene include protein domain specific binding.
Entrez Gene ID
116840
UniProt ID
Q8N137
Alternative Names
Centrobin, Centriole Duplication And Spindle Assembly Protein; Centrobin, Centrosomal BRCA2 Interacting Protein; Centrosomal BRCA2-Interacting Protein; LYST-Interacting Protein 8; Centrobin; LIP8; LYST-Interacting Protein LIP8; PP1221;
Function
Required for centriole duplication. Inhibition of centriole duplication leading to defects in cytokinesis.
Biological Process
Centriole replication Source: HGNC-UCL
Centrosome separation Source: HGNC-UCL
Mitotic cytokinetic process Source: BHF-UCL
Regulation of cilium assembly Source: InterPro
Cellular Location
Centriole. Centriole-associated, asymmetrically localizes to the daughter centriole.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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