Sign in or Register   Sign in or Register
  |  

Rabbit Anti-CPN1 Recombinant Antibody (EPR6229) (CBMAB-C4179WJ)

This product is a Rabbit antibody that recognizes CPN1. This antibody EPR6229 can be used for immunoassay techniques such as: ICC, IHC-P, WB.
See all CPN1 antibodies

Summary

Host Animal
Rabbit
Specificity
Human
Clone
EPR6229
Antibody Isotype
IgG
Application
ICC, IHC-P, WB

Basic Information

Immunogen
A synthetic peptide corresponding to residues in human CPN1 was used as an immunogen
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS 49%, Glycerol 50%, BSA 0.05%
Preservative
0.01% sodium azide
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Carboxypeptidase N Subunit 1
Introduction
CPN1 (Carboxypeptidase N Subunit 1) is a Protein Coding gene. Diseases associated with CPN1 include Carboxypeptidase N Deficiency and Pyelitis. Among its related pathways are Peptide hormone metabolism and Metabolism of proteins. Gene Ontology (GO) annotations related to this gene include metallocarboxypeptidase activity and carboxypeptidase activity. An important paralog of this gene is CPE.
Entrez Gene ID
1369
UniProt ID
P15169
Alternative Names
Carboxypeptidase N Subunit 1; Anaphylatoxin Inactivator; Arginine Carboxypeptidase; Lysine Carboxypeptidase; Carboxypeptidase N, Polypeptide 1; Carboxypeptidase N Small Subunit; Plasma Carboxypeptidase B; Serum Carboxypeptidase N; Carboxypeptidase K; EC 3.4.17.3; Kininase I;
Function
Protects the body from potent vasoactive and inflammatory peptides containing C-terminal Arg or Lys (such as kinins or anaphylatoxins) which are released into the circulation.
Biological Process
Bradykinin catabolic process Source: Ensembl
Peptide metabolic process Source: GO_Central
Protein processing Source: GO_Central
Regulation of complement activation Source: Reactome
Response to glucocorticoid Source: Ensembl
Cellular Location
Extracellular space
Involvement in disease
Carboxypeptidase N deficiency (CPND):
Patients affected present some combination of angioedema or chronic urticaria, as well as hay fever or asthma, and have also slightly depressed serum carboxy peptidase N, suggestive of autosomal recessive inheritance of this disorder.
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Rabbit Anti-CPN1 Recombinant Antibody (EPR6229)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare