Mouse Anti-CPPED1 Recombinant Antibody (CBLC178-LY) (CBMAB-C11137-LY)

The product is antibody recognizes CPPED1. The antibody CBLC178-LY immunoassay techniques such as: WB, IP, IF, ELISA.
See all CPPED1 antibodies

Datasheet

Summary

Host Animal

Mouse

Specificity

Mouse, Rat, Human

Clone

CBLC178-LY

Antibody Isotype

IgG

Application

WB, IP, IF, ELISA

Basic Information

Specificity

Mouse, Rat, Human

Antibody Isotype

IgG

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name

Calcineurin Like Phosphoesterase Domain Containing 1

Introduction

CPPED1 (Calcineurin Like Phosphoesterase Domain Containing 1) is a Protein Coding gene. Among its related pathways are Innate Immune System. Gene Ontology (GO) annotations related to this gene include hydrolase activity and phosphoprotein phosphatase activity.

Entrez Gene ID

Human	55313
Mouse	223978
Rat	302890

UniProt ID

Human	Q9BRF8
Mouse	Q8BFS6
Rat	Q66H71

Function

Protein phosphatase that dephosphorylates AKT family kinase specifically at 'Ser-473', blocking cell cycle progression and promoting cell apoptosis. May play an inhibitory role in glucose uptake by adipocytes.

Biological Process

Neutrophil degranulation Source: Reactome

Cellular Location

Cytoplasm

References

Haapalainen, A. M., Daddali, R., Hallman, M., & Rämet, M. (2021). Human CPPED1 belongs to calcineurin‐like metallophosphoesterase superfamily and dephosphorylates PI3K‐AKT pathway component PAK4. Journal of cellular and molecular medicine, 25(13), 6304-6317.

Daddali, R., Ojaniemi, M., Hallman, M., Rämet, M., & Haapalainen, A. M. (2020). CPPED1-targeting microRNA-371a-5p expression in human placenta associates with spontaneous delivery. Plos one, 15(6), e0234403.

Haapalainen, A. M., Karjalainen, M. K., Daddali, R., Ohlmeier, S., Anttonen, J., Määttä, T. A., ... & Rämet, M. (2018). Expression of CPPED 1 in human trophoblasts is associated with timing of term birth. Journal of cellular and molecular medicine, 22(2), 968-981.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Associated Products

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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Datasheet
SDS
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