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Mouse Anti-CPSF2 Recombinant Antibody (CBXC-1743) (CBMAB-C5839-CQ)

This product is a mouse antibody that recognizes CPSF2. The antibody CBXC-1743 can be used for immunoassay techniques such as: WB, IP, IF, ELISA.
See all CPSF2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXC-1743
Antibody Isotype
IgG
Application
WB, IP, IF, ELISA

Basic Information

Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Cleavage And Polyadenylation Specific Factor 2
Introduction
CPSF2 (Cleavage And Polyadenylation Specific Factor 2) is a Protein Coding gene. Among its related pathways are mRNA Splicing - Major Pathway and RNA Polymerase II Transcription Termination. Gene Ontology (GO) annotations related to this gene include RNA binding.
Entrez Gene ID
53981
UniProt ID
Q9P2I0
Alternative Names
Cleavage And Polyadenylation Specific Factor 2; Cleavage And Polyadenylation Specificity Factor 100 KDa Subunit; Cleavage And Polyadenylation Specific Factor 2, 100kDa; CPSF 100 KDa Subunit; CPSF100; Cleavage And Polyadenylation Specific Factor 2, 100kD Subunit; Cleavage And Polyadenylation Specificity Factor Subunit 2; CPSF 100kDa Subunit; KIAA1367;
Function
Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. Involved in the histone 3' end pre-mRNA processing.
Biological Process
mRNA 3'-end processing Source: Reactome
mRNA 3'-end processing by stem-loop binding and cleavage Source: UniProtKB
mRNA export from nucleus Source: Reactome
mRNA polyadenylation Source: GO_Central
mRNA splicing, via spliceosome Source: Reactome
Pre-mRNA cleavage required for polyadenylation Source: GO_Central
Termination of RNA polymerase II transcription Source: Reactome
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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