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Rabbit Anti-CREBZF Recombinant Antibody (EG825) (CBMAB-EN982-LY)

The product is antibody recognizes CREBZF. The antibody EG825 immunoassay techniques such as: WB: 1:500~1:1000 IF: 1:100~1:500 ELISA: 1:5000.
See all CREBZF antibodies

Summary

Host Animal
Rabbit
Specificity
Human, Mouse
Clone
EG825
Antibody Isotype
IgG
Application
WB: 1:500~1:1000 IF: 1:100~1:500 ELISA: 1:5000

Basic Information

Immunogen
The antibody was produced against synthesized peptide derived from internal of human CREBZF.
Specificity
Human, Mouse
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
CREB/ATF BZIP Transcription Factor
Introduction
CREBZF (CREB/ATF BZIP Transcription Factor) is a Protein Coding gene. Among its related pathways are B Cell Receptor Signaling Pathway (sino) and MAPK-Erk Pathway. Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity and identical protein binding.
Entrez Gene ID
Human58487
Mouse233490
UniProt ID
HumanQ9NS37
MouseQ91ZR3
Alternative Names
CREB/ATF BZIP Transcription Factor; Host Cell Factor-Binding Transcription Factor Zhangfei; HCF-Binding Transcription Factor Zhangfei; Zhangfei; ZF; SHP-Interacting Leucine Zipper Protein; SMILE;
Function
Strongly activates transcription when bound to HCFC1. Suppresses the expression of HSV proteins in cells infected with the virus in a HCFC1-dependent manner. Also suppresses the HCFC1-dependent transcriptional activation by CREB3 and reduces the amount of CREB3 in the cell. Able to down-regulate expression of some cellular genes in CREBZF-expressing cells.
Biological Process
Negative regulation of gene expression, epigenetic Source: UniProtKB
Negative regulation of transcription, DNA-templated Source: UniProtKB
Regulation of DNA-binding transcription factor activity Source: UniProtKB
Regulation of transcription by RNA polymerase II Source: GO_Central
Response to virus Source: UniProtKB
Cellular Location
Nucleus. Colocalizes in promyelocytic leukemia protein nuclear bodies (PML-NB) with CREB3 and HCFC1.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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